Each capsule contains: Collagen Bovine 400 mg.
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Below is general information about the effectiveness of the known ingredients contained in the product Collagen. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product Collagen. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
POSSIBLY SAFE ...when used orally, topically, subcutaneously, or intramuscularly and appropriately. Bovine cartilage has been used orally, topically, subcutaneously, and intramuscularly for up to five years without significant adverse effects (2009,2010,36960,92771). Orally, up to 9 grams daily has been used without evidence of toxicity (2010). Subcutaneously, up to 40 grams weekly and 300 grams total have been injected without evidence of toxicity (2009). Intramuscularly, a complex including bovine cartilage and bone marrow (Rumalon, Robapharm) has been used safely when given in a total of ten treatment courses over five years (92771). However, since these preparations are derived from animals, there is concern about contamination with diseased animal parts (see Adverse Reactions) (1825). So far, there are no reports of disease transmission to humans due to use of contaminated bovine cartilage.
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid
using.
Below is general information about the interactions of the known ingredients contained in the product Collagen. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Below is general information about the adverse effects of the known ingredients contained in the product Collagen. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General
...Orally, subcutaneously, and intramuscularly, bovine cartilage seems to be well tolerated.
Most Common Adverse Effects:
Orally: Fatigue, gastrointestinal upset, and osmotic diarrhea.
Injected: When administered subcutaneously or intramuscularly, bovine cartilage might initially cause a local allergic reaction, manifesting as local redness, swelling, and itching.
Serious Adverse Effects (Rare):
Injected: Nephrotic syndrome.
Gastrointestinal ...Orally, bovine cartilage can cause gastrointestinal upset and osmotic diarrhea (2009).
Genitourinary ...Orally, bovine cartilage can cause scrotal edema (2009).
Immunologic ...Local allergic reactions, manifesting as local redness, swelling, and itching, have been reported in patients receiving intramuscular or subcutaneous injections of bovine cartilage (2010,92771). However, rates of these adverse events in one study were similar to placebo (92771).
Neurologic/CNS ...Orally, bovine cartilage can cause fatigue (2009).
Renal ...When injected, cases of nephrotic syndrome have been reported with a preparation containing bovine cartilage and an extract of bovine marrow (36967,36966,36968).
