Standardized Broccoli Sprout powder.
Brand name products often contain multiple ingredients. To read detailed information about each ingredient, click on the link for the individual ingredient shown above.
This is a "branded ingredient." This means that it is an ingredient used in other companies' products. For example, this product might be just one ingredient used in another company's product that contains multiple ingredients. These branded ingredients usually are not available for sale as stand alone products for consumers.
Below is general information about the effectiveness of the known ingredients contained in the product BroccoPlus. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product BroccoPlus. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
LIKELY SAFE ...when used orally in amounts commonly found in foods. Broccoli sprout is considered safe for dietary consumption. However, broccoli sprouts should be grown in accordance with food safety recommendations developed by the US Food and Drug Administration (FDA) (26424). There is evidence that improperly grown broccoli sprouts are at a higher risk of being contaminated with bacteria, including Listeria monocytogenes (26423), Salmonella (26424,26425), or Escherichia coli O157:H7 (26424,26425).
POSSIBLY SAFE ...when broccoli sprout extract is used orally and appropriately, short-term. Broccoli sprout extract standardized to contain glucosinolate 25-100 mcmol or isothiocyanate 25 mcmol appears to be safe when used three times daily for up to 7 days (26422). Also, broccoli sprout extract providing glucoraphanin 30 mg daily appears to be safe when used daily for 2 months (102154).
PREGNANCY AND LACTATION: LIKELY SAFE
when COOKED broccoli sprouts are consumed in amounts commonly found in foods.
Broccoli sprout is considered safe for dietary consumption provided the sprouts are grown in accordance with food safety recommendations developed by the US Food and Drug Administration (FDA) and are cooked prior to eating (26424).
PREGNANCY AND LACTATION: POSSIBLY UNSAFE
when RAW broccoli sprouts are consumed in amounts commonly found in foods.
There is evidence that uncooked broccoli sprouts may be contaminated with bacteria, including Listeria monocytogenes (26423), Salmonella (26424,26425), or Escherichia coli O157:H7 (26424,26425). Pregnant individuals are particularly susceptible to these food-borne illnesses, and becoming infected can increase the risk of miscarriage, stillbirth, premature birth, or neonatal infection (26170). There is insufficient reliable information available about the safety of broccoli sprout extract during pregnancy or lactation; avoid using.
Below is general information about the interactions of the known ingredients contained in the product BroccoPlus. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
 Details
Animal research shows that broccoli sprout extract can increase CYP1A2 gene expression (95721). Also, pharmacokinetic research in humans shows that eating 500 grams of fresh broccoli daily for 6-12 days can increase CYP1A2 activity by 10% to 200% (19608,95722). Induction of CYP1A2 activity by broccoli is attributed to glucosinolate constituents, which are also found in broccoli sprout (19608).
|
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP2A6.
Details
Pharmacokinetic research in humans shows that eating broccoli 500 grams daily for 6 days increases CYP2A6 activity by 135% to 550%. Induction of CYP2A6 is attributed to glucosinolate constituents, which are also found in broccoli sprout (19608).
|
Below is general information about the adverse effects of the known ingredients contained in the product BroccoPlus. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General ...Orally, properly grown broccoli sprouts are well tolerated when consumed as foods (26424). However, improperly grown broccoli sprouts may be contaminated with bacteria. Broccoli sprout extract seems to be well tolerated (26422). However, a thorough evaluation of safety outcomes has not been conducted.
Gastrointestinal ...Orally, loose stools, diarrhea, abdominal pain, and abdominal cramping have been reported following intake of broccoli seed and broccoli sprout extracts, particularly at high doses (114753). Consuming raw broccoli sprouts that have been improperly grown may cause food-borne illness. Improperly grown broccoli sprouts may be contaminated with bacteria, including Listeria monocytogenes (26423), Salmonella (26424,26425), or Escherichia coli O157:H7 (26424,26425). Cooking broccoli sprouts eliminates this risk.
