Scilla maritima 3 DH. Other Ingredients: Lactose. Sucrose.
Brand name products often contain multiple ingredients. To read detailed information about each ingredient, click on the link for the individual ingredient shown above.
In 2004, Canada began regulating natural medicines as a category of products separate from foods or drugs. These products are officially recognized as "Natural Health Products." These products include vitamins, minerals, herbal preparations, homeopathic products, probiotics, fatty acids, amino acids, and other naturally derived supplements.
In order to be marketed in Canada, natural health products must be licensed. In order to be licensed in Canada, manufacturers must submit applications to Health Canada including information about uses, formulation, dosing, safety, and efficacy.
Products can be licensed based on several criteria. Some products are licensed based on historical or traditional uses. For example, if an herbal product has a history of traditional use, then that product may be acceptable for licensure. In this case, no reliable scientific evidence is required for approval.
For products with non-traditional uses, some level of scientific evidence may be required to support claimed uses. However, a high level of evidence is not necessarily required. Acceptable sources of evidence include at least one well-designed, randomized, controlled trial; well-designed, non-randomized trials; cohort and case control studies; or expert opinion reports.
Finished products licensed by Health Canada must be manufactured according to Good Manufacturing Practices (GMPs) as outlined by Health Canada.
This is a homeopathic preparation. Homeopathy is a system of medicine established in the 19th century by a German physician named Samuel Hahnemann. Its basic principles are that "like treats like" and "potentiation through dilution." For example, in homeopathy, diarrhea would be treated with an extreme dilution of a substance that normally causes diarrhea when taken in high doses.
Practitioners of homeopathy believe that more dilute preparations are more potent. Many homeopathic preparations are so diluted that they contain little or no active ingredient. Therefore, most homeopathic products are not expected to have any pharmacological effects, drug interactions, or other harmful effects. Any beneficial effects are controversial and cannot be explained by current scientific methods.
Dilutions of 1 to 10 are designated by an "X." So a 1X dilution = 1:10, 3X=1:1000; 6X=1:1,000,000. Dilutions of 1 to 100 are designated by a "C." So a 1C dilution = 1:100; 3C = 1:1,000,000. Dilutions of 24X or 12C or more contain zero molecules of the original active ingredient.
Homeopathic products are permitted for sale in the US due to legislation passed in 1938 sponsored by a homeopathic physician who was also a Senator. The law still requires that the FDA allow the sale of products listed in the Homeopathic Pharmacopeia of the United States. However, homeopathic preparations are not held to the same safety and effectiveness standards as conventional medicines. For more information, see the Homeopathy monograph.
Below is general information about the effectiveness of the known ingredients contained in the product Scilla Maritima (Granule). Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product Scilla Maritima (Granule). Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
POSSIBLY SAFE ...when used topically (104983). Squill 2% solution has been applied to the scalp with apparent safety for up to 12 weeks (104983).
UNSAFE ...when used orally (4,6,18,512). Squill contains cardiac glycosides that can cause serious adverse effects (512).
PREGNANCY: UNSAFE
when used orally because it can have an abortifacient effect (4).
Below is general information about the interactions of the known ingredients contained in the product Scilla Maritima (Granule). Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Squill contains cardiac glycosides. Concomitant use of corticosteroids and squill might increase effects and adverse effects of long-term corticosteroid use due to potassium depletion and electrolyte imbalance (2).
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Squill contains cardiac glycosides. Concomitant use of digoxin and squill is contraindicated due to therapeutic duplication and increased risk of cardiac glycoside toxicity (4).
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Squill contains cardiac glycosides. Theoretically, concomitant use with potassium-depleting diuretics can increase the risk of cardiac glycoside toxicity due to potassium depletion (19). Some diuretics that can deplete potassium include chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, Hydrodiuril, Microzide), and others.
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Macrolide antibiotics appear to increase the gastrointestinal absorption of oral digoxin. Theoretically, concomitant use of macrolide antibiotics might increase the absorption of the cardiac glycosides found in squill (17).
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Quinine may reduce the clearance of oral digoxin. Theoretically, concomitant use of quinine with squill might reduce the clearance of cardiac glycosides found in squill and increase the risk of adverse effects (2).
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Squill contains cardiac glycosides. Concomitant use of squill and stimulant laxatives might increase the risk of cardiac glycoside toxicity due to potassium loss (19).
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Tetracycline antibiotics appear to increase the gastrointestinal absorption of oral digoxin. Theoretically, concomitant use of tetracycline antibiotics might increase the absorption of the cardiac glycosides found in squill (17).
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Below is general information about the adverse effects of the known ingredients contained in the product Scilla Maritima (Granule). Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General
...Squill is generally regarded as unsafe for use.
Any benefits of therapy might not outweigh the risk of toxicity. Orally, squill can cause gastric irritation, loss of appetite, diarrhea, nausea, vomiting, stomach disorders, headache, irregular pulse (18,94852), and convulsions (6). Squill poisoning resembles digoxin poisoning. Symptoms of squill poisoning include restlessness, nausea, vomiting, life-threatening arrhythmias, stupor, vision disorders, depression, confusion, hallucinations, psychosis, seizure, cardiac arrest, asphyxiation, and death (18,3488).
Topically, the fresh squill bulb can cause dermatitis (18).
Cardiovascular
...Orally, squill can cause irregular pulse (18,94852).
Squill poisoning resembles digoxin poisoning. The cardiovascular symptoms of squill poisoning include cardiac arrest and life-threatening arrhythmias, including ventricular tachycardia, atrial tachycardia with atrioventricular block, and ventricular fibrillation (18,3488). In one case report, a 55-year-old woman experienced atrioventricular block and ventricular arrythmias after ingesting two squill bulbs, resulting in death (3488).
Dermatologic ...Topically, the fresh squill bulb can cause dermatitis (18). In one case report, a 52-year-old woman presented with non-allergic irritant contact dermatitis after topical application of a squill preparation to the knee and wrist. The squill preparation was kept under occlusive dressing for 24 hours (94852).
Gastrointestinal ...Orally, squill can cause gastric irritation, loss of appetite, diarrhea, nausea, vomiting, and stomach disorders (18,94852).
Neurologic/CNS
...Orally, squill can cause headache and convulsions (6).
Squill poisoning resembles digoxin poisoning. The neurologic symptoms of squill poisoning include confusion, restlessness, stupor, and seizure (18,3488).
Ocular/Otic ...Squill poisoning resembles digoxin poisoning. The ocular symptoms of squill poisoning include various vision disorders (18,3488).
Psychiatric ...Squill poisoning resembles digoxin poisoning. The psychiatric symptoms of squill poisoning include depression, confusion, hallucinations, and psychosis (18,3488).
