Dill Weed by TerraVita

INSUFFICIENT RELIABLE EVIDENCE to RATE

• Aging skin. Applying dill seed extract to the skin may improve some measures of skin wrinkles, but the overall clinical benefit is small. One clinical study in women with age-related wrinkles around the eyes shows that applying 1% dill seed extract to the face twice daily for 3 months improves skin elasticity and firmness by up to 30%, as well as average wrinkle size by approximately 20%, compared with a placebo formulation. However, the dill formulation does not appear to reduce the number of wrinkles or total wrinkle size (99908).
• Dysmenorrhea. Preliminary clinical research shows that taking dill seed powder 3 grams in two divided doses daily for 3 days, beginning at the onset of pain and repeated over three consecutive menstrual cycles, reduces pain associated with dysmenorrhea by a moderate to large amount when compared with baseline. However, it does not improve other menstrual symptoms (101994). The validity of this finding is limited by the lack of a comparator group.
• Hyperlipidemia. Preliminary clinical research in hyperlipidemic patients with coronary artery disease shows that taking dill 650 mg orally twice daily for 6 weeks in addition to following a cholesterol-lowering diet does not improve levels of total cholesterol, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, or triglycerides (47790). In patients with type 2 diabetes, taking dill leaf powder 3 grams daily for 8 weeks lowers LDL cholesterol and total cholesterol, and increases HDL cholesterol when compared with placebo, but does not affect triglycerides (112061). In a meta-analysis of 7 trials, dill significantly reduced LDL cholesterol in a subgroup of patients over 50 years of age who took doses above 1000 mg daily for at least 8 weeks. The analysis did not find any effect on triglycerides, total cholesterol, or high-density lipoprotein (HDL) cholesterol (112062).
• Labor pain. Preliminary clinical research shows that consuming boiled and filtered dill seeds 10 grams once at the beginning of the active labor phase does not reduce labor pain when compared with routine care. However, the duration of each stage of labor was reduced by up to 50% and there was improvement in dilation and effacement (99907). When compared with oxytocin 10 IU at the beginning of the active phase of labor, taking boiled dill seeds 10 grams reduces the duration of the first stage of labor, but not the second or third stages. It also decreases the occurrence of severe anxiety, but does not improve labor pain, when compared with oxytocin (101993). More evidence is needed to rate dill for these uses.

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LIKELY SAFE ...when used orally in amounts commonly found in foods. Dill has Generally Recognized as Safe (GRAS) status in the US (4912).

POSSIBLY SAFE ...when used orally and appropriately in medicinal amounts (12). There is insufficient reliable information available about the safety of dill when used topically.

PREGNANCY: POSSIBLY UNSAFE
when used in medicinal amounts. Dill seed is used to stimulate menstrual flow (19). Theoretically, dill seed might adversely affect pregnancy.

LACTATION:
Insufficient reliable information available; avoid amounts greater than those found in foods.

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ANTIDIABETES DRUGS Interaction Rating = Moderate Be cautious with this combination. Severity = Moderate •  Occurrence = Possible •  Level of Evidence = D Theoretically, dill extract might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia. Animal research shows that dill extract can reduce blood sugar levels (47799,47817). Monitor blood glucose levels closely. Dose adjustments might be necessary.  Details Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), and others.

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General ...Orally, dill is well tolerated when used in amounts commonly found in foods (4912). Dill seems to be well tolerated when used as medicine (12). However, a thorough evaluation of safety outcomes has not been conducted. Some people are allergic to dill (47751,47753).
Topically, photodermatosis is possible after contact with juice from freshly harvested plants (19). Dill can also cause contact dermatitis (19,47767,47773).

Dermatologic ...Topically, photodermatosis is possible after contact with juice from freshly harvested plants (19).

Immunologic ...Orally, there are case reports of individuals allergic to dill (47751,47753). In one case, symptoms, including swelling around the eyes, itching, rash, and chapped lips, occurred after a delay of 12 hours (47751). In another case, immediate symptoms of anaphylaxis, as well as vomiting and diarrhea, occurred following intake and inhalation of foods cooked with dill (47753).
Topically, dill has resulted in contact dermatitis (47767,47773).

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