Each capsule contains: Octopalean brand Octopamine HCl/Norsynephrine HCl 500 mg. Other Ingredients: Microcrystalline Cellulose, Kosher Gelatin, Titanium Dioxide.
Brand name products often contain multiple ingredients. To read detailed information about each ingredient, click on the link for the individual ingredient shown above.
This product has been discontinued by the manufacturer.
This product has been discontinued by the manufacturer.
Below is general information about the effectiveness of the known ingredients contained in the product Beta 3. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product Beta 3. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
POSSIBLY UNSAFE ...when used orally. Octopamine is chemically similar to synephrine, a stimulant that might cause severe adverse effects in some patients. Health Canada states that, based on pharmacology alone, octopamine can likely be used safely at doses of up to 50 mg daily (91684). However, a clinical evaluation of safety outcomes has not been conducted.
PREGNANCY AND LACTATION:
Insufficient reliable information is available; avoid using.
Below is general information about the interactions of the known ingredients contained in the product Beta 3. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
In humans, octopamine 450-600 mg daily increases blood pressure in hypotensive patients (100089). However, evidence from animal research suggests that octopamine can lower blood pressure (11995). Theoretically, concomitant use of octopamine and antihypertensive drugs might potentiate and/or reduce the activity of antihypertensive drugs.
 Details
Some antihypertensive drugs include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others.
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Octopamine is metabolized by monoamine oxidase. Theoretically, concurrent use of MAOIs with octopamine might increase the effects and side effects of octopamine (11995,100099). Tell patients taking MAOIs to avoid using octopamine. Some MAOIs include phenelzine (Nardil), tranylcypromine (Parnate), and others.
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Octopamine is thought to have stimulant effects (94386). Theoretically, taking octopamine with other stimulant drugs might increase the risk of hypertension and adverse cardiovascular effects.
Details
Some stimulant drugs include amphetamine, caffeine, diethylpropion (Tenuate), methylphenidate, phentermine (Ionamin), pseudoephedrine (Sudafed, others), and many others.
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Below is general information about the adverse effects of the known ingredients contained in the product Beta 3. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General ...Octopamine is chemically similar to synephrine, a stimulant that might cause severe adverse effects in some patients. Due to theoretical concerns for stimulant-related adverse effects, Health Canada has set the maximum daily dose of octopamine at 50 mg (91684). However, clinical evidence on the safety of octopamine at any dose is lacking. In one case report, chronic use of a sports supplement containing octopamine and other ingredients resulted in thrombus and myocardial infarction (100091).
Cardiovascular
...Octopamine is commonly used as a stimulant.
Due to its chemical similarities to synephrine, a stimulant with the potential to cause severe cardiovascular effects, Health Canada has set the maximum daily dose of octopamine at 50 mg (91684). However, clinical evidence on the safety of octopamine at any dose is lacking.
In a previously healthy, 39-year-old man, chronic use of a multi-ingredient sports supplement was associated with the development of a thrombus, angina, and acute myocardial infarction. The product claimed to contain synephrine 40 mg, caffeine 400 mg, and unspecified amounts of octopamine and tyramine, in addition to various other products such as St. John's Wort. It is not clear if these effects were due to octopamine, the other ingredients, the patient's concomitant dehydration, or a combination of these factors (100091).
