Mezereum (mezereon) 3X • Rhus toxicodendron (poison ivy) 3X, 12X, 30X • Croton tiglium (croton oil) 6X • Natrum muriaticum (sodium chloride) 6X, 12X, 30X • Sarsaparilla (wild licorice) 6X • Cantharis (Spanish fly) 8X • Kreosotum (creosote) 10X • Mercurius Solubilis (hahemann's soluble mercury) 10X. Inactive Ingredients: Lactose.
Brand name products often contain multiple ingredients. To read detailed information about each ingredient, click on the link for the individual ingredient shown above.
This product has been discontinued by the manufacturer.
This is a homeopathic preparation. Homeopathy is a system of medicine established in the 19th century by a German physician named Samuel Hahnemann. Its basic principles are that "like treats like" and "potentiation through dilution." For example, in homeopathy, diarrhea would be treated with an extreme dilution of a substance that normally causes diarrhea when taken in high doses.
Practitioners of homeopathy believe that more dilute preparations are more potent. Many homeopathic preparations are so diluted that they contain little or no active ingredient. Therefore, most homeopathic products are not expected to have any pharmacological effects, drug interactions, or other harmful effects. Any beneficial effects are controversial and cannot be explained by current scientific methods.
Dilutions of 1 to 10 are designated by an "X." So a 1X dilution = 1:10, 3X=1:1000; 6X=1:1,000,000. Dilutions of 1 to 100 are designated by a "C." So a 1C dilution = 1:100; 3C = 1:1,000,000. Dilutions of 24X or 12C or more contain zero molecules of the original active ingredient.
Homeopathic products are permitted for sale in the US due to legislation passed in 1938 sponsored by a homeopathic physician who was also a Senator. The law still requires that the FDA allow the sale of products listed in the Homeopathic Pharmacopeia of the United States. However, homeopathic preparations are not held to the same safety and effectiveness standards as conventional medicines. For more information, see the Homeopathy monograph.
Below is general information about the effectiveness of the known ingredients contained in the product NatraBio Cold Sores Relief Tablet. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
There is insufficient reliable information available about the effectiveness of croton seeds.
INSUFFICIENT RELIABLE EVIDENCE to RATE
INSUFFICIENT RELIABLE EVIDENCE to RATE
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product NatraBio Cold Sores Relief Tablet. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
LIKELY UNSAFE ...when used orally. One mL (20 drops) of the oil extracted from the seeds can be fatal (18). Also, the phorbol esters in the oil contain a known carcinogen, as well as co-carcinogens (18). ...when used topically; avoid using (18).
PREGNANCY AND LACTATION: UNSAFE
when used orally (18,19).
Croton seed oil has abortifacient properties (19); avoid using.
POSSIBLY UNSAFE ...when used topically. Acute skin contact can cause redness, swelling, and blistering; prolonged skin contact can lead to necrosis (18).
LIKELY UNSAFE ...when used orally. The plant is poisonous and can cause death (18).
PREGNANCY AND LACTATION: LIKELY UNSAFE
when used orally or topically (18); avoid using.
LIKELY UNSAFE ...when used orally or topically (6). Poison ivy is highly irritant and allergenic (68970).
PREGNANCY AND LACTATION: LIKELY UNSAFE
when used orally or topically (6); avoid using.
LIKELY SAFE ...when used orally in amounts commonly found in foods. Sarsaparilla has Generally Recognized As Safe (GRAS) status for use in foods in the US (4912). There is insufficient reliable information available about the safety of sarsaparilla when taken orally in medicinal amounts.
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using.
Below is general information about the interactions of the known ingredients contained in the product NatraBio Cold Sores Relief Tablet. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Theoretically, concomitant use of sarsaparilla with digoxin might increase the risk of cardiac toxicity.
 Details
|
Theoretically, sarsaparilla might increase the effects and adverse effects of lithium.
Details
Sarsaparilla is thought to have diuretic properties (11). Due to these effects, sarsaparilla might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
|
Below is general information about the adverse effects of the known ingredients contained in the product NatraBio Cold Sores Relief Tablet. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General ...Orally, croton seeds can cause burning of the mouth, vomiting, dizziness, stupor, painful bowel movements, and collapse (18). Topically, croton seed oil can cause itching, burning and blistering of the skin (18).
Dermatologic ...Topically, croton seed oil can cause itching, burning and blistering when applied to the skin (18).
Gastrointestinal ...Orally, croton seeds and the seed oil can cause burning of the mouth, vomiting, and painful bowel movements (18).
Neurologic/CNS ...Orally, croton seed oil can cause dizziness, stupor, and collapse (18).
Other ...Orally, croton seed oil in doses as low as 1 mL (20 drops) can be fatal (18). Additionally, the oil contains phorbol esters, which contain tetradecanolyphorbol acetate, a known carcinogen, as well as co-carcinogens (18).
General
...Orally, mezereon is generally regarded as unsafe for use.
Any benefits of therapy may not outweigh the risk of toxicity. Topically, mezereon can cause significant irritation.
Most Common Adverse Effects:
Orally: Abdominal pain, diarrhea, reddening and swelling of the oral mucous membranes, salivation, thirst, vomiting.
Topically: Blistering, redness, swelling.
Cardiovascular ...Orally, mezereon can cause headache, dizziness, stupor, tachycardia, spasms, and death through circulatory collapse (18).
Dermatologic ...Topically, mezereon can cause red, painful swelling of the skin, blister formation, and shedding of the epidermis (18). Extended exposure can cause necrosis (18). Contact with the eyes can cause severe conjunctivitis (18).
Gastrointestinal ...Orally, mezereon can cause reddening and swelling of the oral mucous membranes, salivation, thirst, stomach pains, vomiting, and severe diarrhea (18).
General
...When used orally or topically, poison ivy may be unsafe.
Most Common Adverse Effects:
Orally: Diarrhea, dizziness, fever, intestinal colic, nausea, vomiting, severe mucous membrane irritation.
Topically: Contact dermatitis, herpes-like blisters, reddening, swelling.
Inhaled: Fever.
Serious Adverse Effects (Rare):
Orally: Fever, hematuria, nephritis, stupor, unconsciousness.
Topically: Erythema multiforme, black spot poison ivy dermatitis. Eye contact can cause severe conjunctivitis, corneal inflammations, or loss of sight.
Inhaled: Lung infection, respiratory distress syndrome, throat swelling.
Dermatologic ...Topically, poison ivy can cause contact dermatitis, reddening, swelling, and herpes-like blisters (18). These reactions occur at the area of contact, usually within a few hours, but are sometimes delayed for several days (68970). Sometimes papules and vesicles develop and can spread beyond the area of initial contact, but are generally self-limiting and eventually form crusts. (3839,68955,68960,68977,69007,69008,69038,69042). In a few cases, small white papules known as milia have developed on an area of poison ivy exposure after the typical skin reaction has subsided (94222). Occasionally, poison ivy causes more severe dermatologic reactions such as erythema multiforme (3839,68983,69032,112851). Black spot poison ivy dermatitis also occurs in rare cases, with black lacquer-like lesions on the skin that cannot be washed off, followed by the typical pruritic papules (112850). The black lesions are concentrated urushiol oleoresin that has darkened with exposure to oxygen and moisture (68960,68997,69027,69034). They eventually peel off and the skin heals normally (68960,112850).
Gastrointestinal ...Orally, poison ivy can cause severe mucous membrane irritation, nausea, vomiting, and diarrhea (18).
Genitourinary ...Orally, poison ivy can cause hematuria (18).
Immunologic ...Cross-allergenicity with poison ivy exists with cashew, mango, and ginkgo biloba (106574).
Neurologic/CNS ...Orally, poison ivy can cause dizziness, fever, stupor, and unconsciousness (18).
Ocular/Otic ...Topically, eye contact with urushiol from poison ivy can cause severe conjunctivitis, corneal inflammation, and potentially loss of sight (18).
Pulmonary/Respiratory ...Inhaled, urushiol in the smoke from burning of poison ivy can result in life-threatening throat swelling, fever, and secondary lung infections (6). Respiratory distress syndrome after smoke inhalation from burning poison ivy has also been reported (69036). Two fatal cases of acute respiratory distress and anaphylaxis after inhaling burned poison ivy are reported in patients with known allergies to poison ivy (112420).
Renal ...Orally, poison ivy can cause nephritis (18).
General ...Orally, sarsaparilla seems to be well tolerated.
Gastrointestinal ...Orally, there is some concern that sarsaparilla may cause GI irritation when used in large amounts (11,18). However, these claims cannot be substantiated.
Pulmonary/Respiratory ...Occupational exposure to sarsaparilla root dust can cause rhinitis and asthma symptoms (4111).
Renal ...Orally, there is some concern that sarsaparilla may cause temporary kidney impairment and diuresis, possibly leading to shock, when used in large amounts (11,18). However, these claims cannot be substantiated.
