References
Evening Primrose
274
Chenoy R, Hussain S, Tayob Y, et al. Effect of oral gamolenic acid from evening primrose oil on menopausal flushing (abstract). BMJ 1994;308:501-3. View abstract.
588
Shuster J. Black cohosh root? Chasteberry Tree? Seizures! Hosp Pharm 1996;31:1553-4.
613
Shaw D, Leon C, Kolev S, Murray V. Traditional remedies and food supplements: a 5-year toxicological study (1991-1995). Drug Saf 1997;17:342-56. View abstract.
1037
Greenfield SM, Green AT, Teare JP, et al. A randomized controlled study of evening primrose oil and fish oil in ulcerative colitis. Aliment Pharmacol Ther 1993;7:159-66. View abstract.
1042
D'Almeida A, Carter JP, Anatol A, Prost C. Effects of a combination of evening primrose oil (gamma linolenic acid) and fish oil (eicosapentaenoic + docahexaenoic acid) versus magnesium, and versus placebo in preventing pre-eclampsia. Women Health 1992;19:117-31. View abstract.
1106
Khoo SK, Munro C, Battistutta D. Evening primrose oil and treatment of premenstrual syndrome. Med J Aust 1990;153:189-92. View abstract.
1407
O'Brien PM, Pipkin FB. The effect of essential fatty acid and specific vitamin supplements on vascular sensitivity in the mid trimester of human pregnancy. Clin Exp Hypertens B 1983;2:247-54. View abstract.
1408
O'Brien PM, Morrison R, Pipken FB. Effect of dietary supplementation with linoleic and gammalinolenic acids on the pressor response to angiotensin II--possible role in pregnancy induced hypertension? Br J Clin Pharmacol 1985;19:335-42. View abstract.
1409
Laivuori H, Hovatta O, Viinikka L, et al. Dietary supplementation with primrose oil or fish oil does not change urinary excretion of prostacyclin and thromboxane metabolites in pre-eclamptic women. Prostaglandins Leukot Essent Fatty Acids 1993;49:691-4. View abstract.
1411
Dove D, Johnson P. Oral evening primrose oil: its effect on length of pregnancy and selected intrapartum outcomes in low-risk nulliparous women (abstract). J Nurse Midwifery 1999;44:320-4. View abstract.
1979
Guivernau M, Meza N, Barja P, Roman O. Clinical and experimental study on the long-term effect of dietary gamma-linolenic acid on plasma lipids, platelet aggregation, thromboxane formation, and prostacyclin production. Prostaglandins Leukot Essent Fatty Acids 1994;51:311-6. View abstract.
1980
Jamal GA. The use of gamma linolenic acid in the prevention and treatment of diabetic neuropathy. Diabet Med 1994;11:145-9. View abstract.
1982
Cant A, Shay J, Horrobin DF. The effect of maternal supplementation with linoleic and gamma- linolenic acids on the fat composition and content of human milk: a placebo-controlled trial. J Nutr Sci Vitaminol (Tokyo) 1991;37:573-9. View abstract.
1983
van der Merwe CF, Booyens J, Joubert HF, van der Merwe CA. The effect of gamma-linolenic acid, an in vitro cytostatic substance contained in evening primrose oil, on primary liver cancer. A double- blind placebo controlled trial. Prostaglandins Leukot Essent Fatty Acids 1990;40:199-202. View abstract.
2039
Morse PF, Horrobin DF, Manku MS, et al. Meta-analysis of placebo-controlled studies of the efficacy of Epogam in the treatment of atopic eczema. Relationship between plasma essential fatty acid changes and clinical response. Br J Dermatol 1989;121:75-90. View abstract.
3908
Kleijnen J. Evening primrose oil. BMJ 1994;309:824-825. View abstract.
3909
Head RJ, McLennan PL, Raederstorff D, et al. Prevention of nerve conduction deficit in diabetic rats by polyunsaturated fatty acids. Am J Clin Nutr 2000;71:386S-392S. View abstract.
5708
Stordy BJ. Dark adaptation, motor skills, docosahexaenoic acid, and dyslexia. Am J Clin Nutr 2000;71:323S-6S. View abstract.
5902
Kenny FS, Pinder SE, Ellis IO, et al. Gamma linolenic acid with tamoxifen as primary therapy in breast cancer. Int J Cancer 2000;85:643-8. View abstract.
6034
Hardy ML. Herbs of special interest to women. J Am Pharm Assoc 200;40:234-42. View abstract.
6036
Belch J, Hill A. Evening primrose oil and borage oil in rheumatologic conditions. Am J Clin Nutr 2000;71:352S-6S. View abstract.
6406
Pye JK, Mansel RE, Hughes LE. Clinical experience of drug treatments for mastalgia. Lancet 1985;2:373-7. View abstract.
6443
Arnold LE, Kleykamp D, Votolato NA, et al. Gamma-linolenic acid for attention-deficit hyperactivity disorder: Placebo-controlled comparison to D-amphetamine. Biol Psychiatry 1989;25:222-8. View abstract.
6462
Aman MG, Mitchell EA, Turbott SH. The effects of essential fatty acid supplementation by Efamol in hyperactive children. J Abnorm Child Psychol 1987;15:75-90. View abstract.
6847
Bendich A. The potential for dietary supplements to reduce premenstrual syndrome (PMS) symptoms. J Am Coll Nutrition 2000;19:3-12. View abstract.
7563
Behan PO, Behan WM, Horrobin D. Effect of high doses of essential fatty acids on the postviral fatigue syndrome. Acta Neurol Scand 1990;82:209-16. View abstract.
7564
Warren G, McKendrick M, Peet M. The role of essential fatty acids in chronic fatigue syndrome. A case-controlled study of red-cell membrane essential fatty acids (EFA) and a placebo-controlled treatment study with high dose of EFA. Acta Neurol Scand 1999;99:112-6. View abstract.
7565
Hederos CA, Berg A. Epogam evening primrose oil treatment in atopic dermatitis and asthma. Arch Dis Child 1996;75:494-7. View abstract.
7566
Berth-Jones J, Graham-Brown RA. Placebo-controlled trial of essential fatty acid supplementation in atopic dermatitis. Lancet 1993;341:1557-60. View abstract.
7567
Whitaker DK, Cilliers J, de Beer C. Evening primrose oil (Epogam) in the treatment of chronic hand dermatitis: disappointing therapeutic results. Dermatology 1996;193:115-20. View abstract.
7568
Bordoni A, Biagi PL, Masi M, et al. Evening primrose oil (Efamol) in the treatment of children with atopic eczema. Drugs Exp Clin Res 1988;14:291-7. View abstract.
7569
Schalin-Karrila M, Mattila L, Jansen CT, Uotila P. Evening primrose oil in the treatment of atopic eczema: effect on clinical status, plasma phospholipid fatty acids and circulating blood prostaglandins. Br J Dermatol 1987;117:11-9. View abstract.
7570
Biagi PL, Bordoni A, Hrelia S, et al. The effect of gamma-linolenic acid on clinical status, red cell fatty acid composition and membrane microviscosity in infants with atopic dermatitis. Drugs Exp Clin Res 1994;20:77-84. View abstract.
7634
Engler MM, Engler MB, Erickson SK, Paul SM. Dietary gamma-linolenic acid lowers blood pressure and alters aortic reactivity and cholesterol metabolism in hypertension. J Hypertens 1992;10:1197-204. View abstract.
8129
Horrobin DF. Evening primrose oil and premenstrual syndrome. Med J Aust 1990;153:630-1. View abstract.
8133
Menendez JA, del Mar Barbacid M, Montero S, et al. Effects of gamma-linolenic acid and oleic acid on paclitaxel cytotoxicity in human breast cancer cells. Eur J Cancer 2001;37:402-13. View abstract.
8522
Roemheld-Hamm B, Dahl NV. Herbs, menopause, and dialysis. Semin Dial 2002;15:53-9.. View abstract.
8926
Keen H, Payan J, Allawi J, et al. Treatment of diabetic neuropathy with gamma-linolenic acid. The gamma-Linolenic Acid Multicenter Trial Group. Diabetes Care 1993;16:8-15. View abstract.
8996
Horner NK, Lampe JW. Potential mechanisms of diet therapy for fibrocystic breast conditions show inadequate evidence of effectiveness. J Am Diet Assoc 2000;100:1368-80. View abstract.
9156
Blommers J, de Lange-De Klerk ES, Kuik DJ, et al. Evening primrose oil and fish oil for severe chronic mastalgia: a randomized, double-blind, controlled trial. Am J Obstet Gynecol 2002;187:1389-94.. View abstract.
9794
Cheung KL. Management of cyclical mastalgia in oriental women: pioneer experience of using gamolenic acid (Efamast) in Asia. Aust N Z J Surg 1999;69:492-4.. View abstract.
9882
The Medicines Control Agency (MCA), Epogam and Efamast (gamolenic acid) - withdrawal of marketing authorizations. http://www.mca.gov.uk/whatsnew/epogam.htm. (Accessed 2 June 2003).
11339
Rose DP, Connolly JM, Liu XH. Effects of linoleic acid and gamma-linolenic acid on the growth and metastasis of a human breast cancer cell line in nude mice and on its growth and invasive capacity in vitro. Nutr Cancer 1995;24:33-45. . View abstract.
11341
Takwale A, Tan E, Agarwal S, et al. Efficacy and tolerability of borage oil in adults and children with atopic eczema: randomised, double blind, placebo controlled, parallel group trial. BMJ 2003;327:1385. View abstract.
11342
Williams HC. Evening primrose oil for atopic dermatitis. BMJ 2003;327:1358-9. View abstract.
11791
Menendez JA, Colomer R, Lupu R. Omega-6 polyunsaturated fatty acid gamma-linolenic acid (18:3n-6) is a selective estrogen-response modulator in human breast cancer cells: gamma-Linolenic acid antagonizes estrogen receptor-dependent transcriptional activity, transcriptionally represses estrogen receptor expression and synergistically enhances tamoxifen and ICI 182,780 (Faslodex) efficacy in human breast cancer cells. Int J Cancer 2004;10;109:949-54. View abstract.
11884
Das UN. The lipids that matter from infant nutrition to insulin resistance. Prostaglandins Leukot Essent Fatty Acids 2002;67:1-12. View abstract.
12035
Hansen TM, Lerche A, Kassis V, et al. Treatment of rheumatoid arthritis with prostaglandin E1 precursors cis-linoleic acid and gamma-linolenic acid. Scand J Rheumatol 1983;12:85-8. View abstract.
12036
Belch JJ, Ansell D, Madhok R, et al. Effects of altering dietary essential fatty acids on requirements for non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis: A double blind placebo controlled study. Ann Rheum Dis 1988;47:96-104. View abstract.
12037
Oxholm P, Manthorpe R, Prause JU, Horrobin D. Patients with primary Sjogren's syndrome treated for two months with evening primrose oil. Scan J Rheumatol 1986;15:103-8. View abstract.
12038
McKendry RJ. Treatment of Sjogren's syndrome with essential fatty acids, pyridoxine and vitamin C. Prostaglandins Leukot Med 1982;8:403-8. View abstract.
12470
Furse RK, Rossetti RG, Seiler CM, Zurier RB. Oral administration of gammalinolenic acid, an unsaturated fatty acid with anti-inflammatory properties, modulates interleukin-1beta production by human monocytes. J Clin Immunol 2002;22:83-91. View abstract.
13758
van Gool CJ, Zeegers MP, Thijs C. Oral essential fatty acid supplementation in atopic dermatitis-a meta-analysis of placebo-controlled trials. Br J Dermatol 2004;150:728-40. View abstract.
15739
Sinn N, Bryan J. Effect of Supplementation with Polyunsaturated Fatty Acids and Micronutrients on Learning and Behavior Problems Associated with Child ADHD. J Dev Behav Pediatr 2007;28:82-91. View abstract.
16303
Wedig KE, Whitsett JA. Down the primrose path: petechiae in a neonate exposed to herbal remedy for parturition. J Pediatr 2008;152:140, 140.e1. View abstract.
20511
Gehring W, Bopp R, Rippke F, and Gloor M. Effect of topically applied evening primrose oil on epidermal barrier function in atopic dermatitis as a function of vehicle. Arzneimittelforschung. 1999;49(7):635-642. View abstract.
20512
Senapati S, Banerjee S, and Gangopadhyay DN. Evening primrose oil is effective in atopic dermatitis: a randomized placebo-controlled trial. Indian J Dermatol.Venereol.Leprol. 2008;74(5):447-452. View abstract.
20515
Wright S. Atopic dermatitis and essential fatty acids: a biochemical basis for atopy? Acta Derm Venereol Suppl (Stockh) 1985;114:143-145. View abstract.
20517
Srivastava A, Mansel RE, Arvind N, Prasad K, Dhar A, and Chabra A. Evidence-based management of Mastalgia: a meta-analysis of randomised trials. Breast 2007;16(5):503-512. View abstract.
20518
Pruthi S, Wahner-Roedler DL, Torkelson CJ, Cha SS, Thicke LS, Hazelton JH, and Bauer BA. Vitamin E and evening primrose oil for management of cyclical mastalgia: a randomized pilot study. Altern Med Rev 2010;15(1):59-67. View abstract.
20519
Mansel RE, Pye JK Hughes LE. Effects of essential fatty acids on cyclical mastalgia and non-cyclical breast disorders. In: Horrobin DF. Omega-6 essential fatty acids: pathophysiology and roles in clinical medicine. New York: Wiley-Liss;1990.
20520
Pashby N, Mansel R, Hughes L, and et al. A clinical trial of evening primrose in mastalgia. Br J Surg 1981;68:801.
20521
Saied GM, Kamel RM, and Dessouki N. Low intensity laser therapy is comparable to bromocriptine-evening primrose oil for the treatment of cyclical mastalgia in Egyptian females. Tanzan Health Res Bull 2007;9(3):196-201. View abstract.
20522
Abraham RD, Riemersma RA, Elton RA, et al. Effects of safflower oil and evening primrose oil in men with a low dihomo-gamma-linolenic level. Atherosclerosis 1990;81:199-208. View abstract.
20523
Viikari J and Lehtonen A. Effect of primrose oil on serum lipids and blood pressure in hyperlipidemic subjects. Int J Clin Pharmacol Ther Toxicol 1986;2:668-670. View abstract.
20524
Ty-Torredes KA. The effect of oral evening primrose oil on bishop score and cervical length amongst term gravidas. Am J Obstet Gynecol. 2006;195(6 Suppl 1):S30.
20525
Moodley J and Norman RJ. Attempts at dietary alteration of prostaglandin pathways in the management of pre-eclampsia. Prostaglandins Leukot Essent Fatty Acids 1989;37(3):145-147. View abstract.
20528
Jamal GA and Carmichael H. The effects of gamma-linolenic acid on human diabetic peripheral neuropathy: a double-blind placebo-controlled trial. Diabet Med 1990;7(4):319-323. View abstract.
20530
Lindmark L and Clough P. A 5-month open study with long-chain polyunsaturated fatty acids in dyslexia. J Med Food 2007;10(4):662-6. View abstract.
20531
Kokke KH, Morris JA, and Lawrenson JG. Oral omega-6 essential fatty acid treatment in contact lens associated dry eye. Cont Lens Anterior Eye 2008;31(3):141-146. View abstract.
20532
Ishikawa T, Fujiyama Y, Igarashi O, Morino M, Tada N, Kagami A, Sakamoto T, Nagano M, and Nakamura H. Effects of gammalinolenic acid on plasma lipoproteins and apolipoproteins. Atherosclerosis 1989;75:95-104. View abstract.
20533
Tong M. [Treatment of hyperlipemia with evening primrose oil capsules]. Zhong Xi Yi Jie He Za Zhi. 1988;8:469-71, 452-3. View abstract.
20534
Tang W, Song YF He ZM. Clinical observation of Blackcurrant oil Soft Capsule and Evening primrose oil Soft Capsule in treating hyperlipidemia. Acta Chinese Medicine and Pharmacology 1993;21(4):37-38.
20535
Liang XC and Guo SS. [Effect of jiang-zhi zhong-yao-pian on total cholesterol, triglyceride, TXB2, 6-keto-PGF1 alpha in hyperlipemic patients]. Zhong Xi Yi Jie He Za Zhi 1991;11:20-2, 4. View abstract.
20536
Gupta H, Pawar D, Riva A, et al. A randomized, double-blind, placebo-controlled trial to evaluate efficacy and tolerability of an optimized botanical combination in the management of patients with primary hypercholesterolemia and mixed dyslipidemia. Phytother Res 2012;26:265-272. View abstract.
20537
Chalmers RJ and Shuster S. Evening primrose seed oil in ichthyosis vulgaris. Lancet 1-29-1983;1(8318):236-237. View abstract.
20540
Haslett C, Douglas JG, Chalmers SR, Weighhill A, and Munro JF. A double-blind evaluation of evening primrose oil as an antiobesity agent. Int.J Obes 1983;7(6):549-553. View abstract.
20541
Belch JJ, Shaw B, O'Dowd A, Saniabadi A, Leiberman P, Sturrock RD, and Forbes CD. Evening primrose oil (Efamol) in the treatment of Raynaud's phenomenon: a double blind study. Thromb.Haemost. 8-30-1985;54(2):490-494. View abstract.
20542
Brzeski M, Madhok R, and Capell HA. Evening primrose oil in patients with rheumatoid arthritis and side- effects of non-steroidal anti-inflammatory drugs. Br J Rheumatol 1991;30(5):370-372. View abstract.
20543
Jantti J, Seppala E, Vapaatalo H, and Isomaki H. Evening primrose oil and olive oil in treatment of rheumatoid arthritis. Clin Rheumatol 1989;8(2):238-244. View abstract.
20544
Veale DJ, Torley HI, Richards IM, O'Dowd A, Fitzsimons C, Belch JJ, and Sturrock RD. A double-blind placebo controlled trial of Efamol Marine on skin and joint symptoms of psoriatic arthritis. Br J Rheumatol 1994;33(10):954-958. View abstract.
20545
Ebden P, Bevan C, Banks J, Fennerty A, and Walters EH. A study of evening primrose seed oil in atopic asthma. Prostaglandins Leukot Essent Fatty Acids 1989;35(2):69-72. View abstract.
20546
Stenius-Aarniala B, Aro A, Hakulinen A, Ahola I, Seppala E, and Vapaatalo H. Evening primrose oil and fish oil are ineffective as supplementary treatment of bronchial asthma. Ann Allergy 1989;62(6):534-537. View abstract.
20548
Jenkins AP, Green AT, and Thompson RP. Essential fatty acid supplementation in chronic hepatitis B. Aliment Pharmacol Ther 1996;10(4):665-668. View abstract.
20549
Makrides M, Neumann M, Simmer K, Pater J, and Gibson R. Are long-chain polyunsaturated fatty acids essential nutrients in infancy? Lancet 1995;345(8963):1463-1468. View abstract.
21001
Bassey EJ, Littlewood JJ, Rothwell MC, and Pye DW. Lack of effect of supplementation with essential fatty acids on bone mineral density in healthy pre- and postmenopausal women: two randomized controlled trials of Efacal v. calcium alone. Br J Nutr 2000;83(6):629-635. View abstract.
21002
Cancelo Hidalgo MJ, Castelo-Branco C, Blumel JE, Lanchares Perez J.L, and Alvarez De Los Heros JI. Effect of a compound containing isoflavones, primrose oil and vitamin E in two different doses on climacteric symptoms. J Obstet Gynaecol 2006;26(4):344-347. View abstract.
21004
Collins A, Cerin A, Coleman G, and Landgren BM. Essential fatty acids in the treatment of premenstrual syndrome. Obstet Gynecol 1993;81(1):93-98. View abstract.
21005
Puolakka J, Makarainen L, Viinikka L, and Ylikorkala O. Biochemical and clinical effects of treating the premenstrual syndrome with prostaglandin synthesis precursors. J Reprod Med 1985;30(3):149-153. View abstract.
21006
Strong A and Hamill E. The effect of combined fish oil and evening primrose oil (Efamol Marine) on the remission phase of psoriasis: a 7-month double-blind randomized placebo-controlled trial. Journal of Dermatological Treatment 1993;4:33-36.
21007
Oliwiecki S and Burton JL. Evening primrose oil and marine oil in the treatment of psoriasis. Clin Exp Dermatol 1994;19(2):127-129.. View abstract.
21009
Vaddadi KS, Courtney P, Gilleard CJ, Manku MS, and Horrobin DF. A double-blind trial of essential fatty acid supplementation in patients with tardive dyskinesia. Psychiatry Res 1989;27(3):313-323. View abstract.
21010
Holman CP and Bell AF. A trial of evening primrose oil in the treatment of chronic schizophrenia. J Orhtomolecular Psych 1983;12:302-304.
21013
Vaddadi KS. The use of gamma-linolenic acid and linoleic acid to differentiate between temporal lobe epilepsy and schizophrenia. Prostaglandins Med 1981;6(4):375-379. View abstract.
21017
Zou L, Harkey MR, and Henderson GL. Effects of herbal components on cDNA-expressed cytochrome P450 enzyme catalytic activity. Life Sci 8-16-2002;71(13):1579-1589. View abstract.
21019
Lovell CR, Burton JL, and Horrobin DF. Treatment of atopic eczema with evening primrose oil. Lancet 1-31-1981;1(8214):278. View abstract.
49174
Woltil, H. A., van Beusekom, C. M., Schaafsma, A., Okken, A., and Muskiet, F. A. Does supplementation of formula with evening primrose and fish oils augment long chain polyunsaturated fatty acid status of low birthweight infants to that of breast-fed counterparts? Prostaglandins Leukot.Essent.Fatty Acids 1999;60(3):199-208. View abstract.
49175
Endres, S., Lorenz, R., and Loeschke, K. Lipid treatment of inflammatory bowel disease. Curr Opin.Clin Nutr Metab Care 1999;2(2):117-120. View abstract.
49182
Hoare, C., Li Wan, Po A., and Williams, H. Systematic review of treatments for atopic eczema. Health Technol Assess 2000;4(37):1-191. View abstract.
49187
Taylor, M. Botanicals: medicines and menopause. Clin Obstet.Gynecol. 2001;44(4):853-863. View abstract.
49188
Yoon, S., Lee, J., and Lee, S. The therapeutic effect of evening primrose oil in atopic dermatitis patients with dry scaly skin lesions is associated with the normalization of serum gamma-interferon levels. Skin Pharmacol Appl.Skin Physiol 2002;15(1):20-25. View abstract.
49189
Langmead, L., Chitnis, M., and Rampton, D. S. Use of complementary therapies by patients with IBD may indicate psychosocial distress. Inflamm.Bowel.Dis 2002;8(3):174-179. View abstract.
49193
Conquer, J. A., Roelfsema, H., Zecevic, J., Graham, T. E., and Holub, B. J. Effect of exercise on FA profiles in n-3 FA-supplemented and -nonsupplemented premenopausal women. Lipids 2002;37(10):947-951. View abstract.
49194
Halat, K. M. and Dennehy, C. E. Botanicals and dietary supplements in diabetic peripheral neuropathy. J Am Board Fam.Pract. 2003;16(1):47-57. View abstract.
49195
Barabino, S., Rolando, M., Camicione, P., Ravera, G., Zanardi, S., Giuffrida, S., and Calabria, G. Systemic linoleic and gamma-linolenic acid therapy in dry eye syndrome with an inflammatory component. Cornea 2003;22(2):97-101. View abstract.
49201
McFayden, I. J., Forrest, A. P., Chetty, U., and Raab, G. Cyclical breast pain--some observations and the difficulties in treatment. Br.J Clin Pract. 1992;46(3):161-164. View abstract.
49208
Smith, R. L., Pruthi, S., and Fitzpatrick, L. A. Evaluation and management of breast pain. Mayo Clin Proc. 2004;79(3):353-372. View abstract.
49209
Gateley, C. A., Miers, M., Mansel, R. E., and Hughes, L. E. Drug treatments for mastalgia: 17 years experience in the Cardiff Mastalgia Clinic. J R.Soc Med 1992;85(1):12-15. View abstract.
49212
Goyal, A. and Mansel, R. E. A randomized multicenter study of gamolenic acid (Efamast) with and without antioxidant vitamins and minerals in the management of mastalgia. Breast J 2005;11(1):41-47. View abstract.
49213
Gimenes, O. M., da Silva, M. J., and Benko, M. A. [Flower essences: vibrational intervention of diagnostic and therapeutic possibilities]. Rev.Esc Enferm.USP. 2004;38(4):386-395. View abstract.
49214
Qureshi, S. and Sultan, N. Topical nonsteroidal anti-inflammatory drugs versus oil of evening primrose in the treatment of mastalgia. Surgeon. 2005;3(1):7-10. View abstract.
49215
Gateley, C. A., Maddox, P. R., Pritchard, G. A., Sheridan, W., Harrison, B. J., Pye, J. K., Webster, D. J., Hughes, L. E., and Mansel, R. E. Plasma fatty acid profiles in benign breast disorders. Br J Surg. 1992;79(5):407-409. View abstract.
49216
Pellegrina, C. D., Padovani, G., Mainente, F., Zoccatelli, G., Bissoli, G., Mosconi, S., Veneri, G., Peruffo, A., Andrighetto, G., Rizzi, C., and Chignola, R. Anti-tumour potential of a gallic acid-containing phenolic fraction from Oenothera biennis. Cancer Lett. 8-8-2005;226(1):17-25. View abstract.
49218
Aragona, P., Bucolo, C., Spinella, R., Giuffrida, S., and Ferreri, G. Systemic omega-6 essential fatty acid treatment and pge1 tear content in Sjogren's syndrome patients. Invest Ophthalmol.Vis.Sci 2005;46(12):4474-4479. View abstract.
49219
Gruenwald, J., Graubaum, H. J., and Busch, R. Efficacy and tolerability of a fixed combination of thyme and primrose root in patients with acute bronchitis. A double-blind, randomized, placebo-controlled clinical trial. Arzneimittelforschung 2005;55(11):669-676. View abstract.
49220
Rosolowich, V., Saettler, E., Szuck, B., Lea, R. H., Levesque, P., Weisberg, F., Graham, J., McLeod, L., and Rosolowich, V. Mastalgia. J Obstet.Gynaecol.Can 2006;28(1):49-71. View abstract.
49221
Whelan, A. M., Jurgens, T. M., and Bowles, S. K. Natural health products in the prevention and treatment of osteoporosis: systematic review of randomized controlled trials. Ann Pharmacother 2006;40(5):836-849. View abstract.
49223
Gruenwald, J., Graubaum, H. J., and Busch, R. Evaluation of the non-inferiority of a fixed combination of thyme fluid- and primrose root extract in comparison to a fixed combination of thyme fluid extract and primrose root tincture in patients with acute bronchitis. A single-blind, randomized, bi-centric clinical trial. Arzneimittelforschung 2006;56(8):574-581. View abstract.
49224
Kemmerich, B. Evaluation of efficacy and tolerability of a fixed combination of dry extracts of thyme herb and primrose root in adults suffering from acute bronchitis with productive cough. A prospective, double-blind, placebo-controlled multicentre clinical trial. Arzneimittelforschung 2007;57(9):607-615. View abstract.
49225
Gateley, C. A. and Mansel, R. E. Management of the painful and nodular breast. Br Med Bull. 1991;47(2):284-294. View abstract.
49226
Stonemetz, D. A review of the clinical efficacy of evening primrose. Holist.Nurs.Pract. 2008;22(3):171-174. View abstract.
49227
Namaka, M., Crook, A., Doupe, A., Kler, K., Vasconcelos, M., Klowak, M., Gong, Y., Wojewnik-Smith, A., and Melanson, M. Examining the evidence: complementary adjunctive therapies for multiple sclerosis. Neurol.Res 2008;30(7):710-719. View abstract.
49228
Murray, T., Kelsberg, G., Safranek, S., and Crawford, P. Clinical inquiries. Do any folk remedies or herbals help induce labor? J Fam.Pract. 2008;57(8):542-544. View abstract.
49229
Arisaka, M., Arisaka, O., and Yamashiro, Y. Fatty acid and prostaglandin metabolism in children with diabetes mellitus. II. The effect of evening primrose oil supplementation on serum fatty acid and plasma prostaglandin levels. Prostaglandins Leukot.Essent.Fatty Acids 1991;43(3):197-201. View abstract.
49230
Ring, J. and Kleinheinz, A. [Evening primrose oil in neurodermatitis?]. Med Monatsschr.Pharm. 1991;14(9):282. View abstract.
49231
Sharpe, G. R. and Farr, P. M. Evening primrose oil and eczema. Lancet 3-17-1990;335(8690):667-668. View abstract.
49233
Horrobin, D. F. and Stewart, C. Evening primrose oil in atopic eczema. Lancet 4-7-1990;335(8693):864-865. View abstract.
49234
Sharpe, G. R. and Farr, P. M. Evening primrose oil and eczema. Lancet 5-26-1990;335(8700):1283. View abstract.
49235
Platzbecker, U., Aul, C., Ehninger, G., and Giagounidis, A. Reduction of 5-azacitidine induced skin reactions in MDS patients with evening primrose oil. Ann Hematol. 2010;89(4):427-428. View abstract.
49236
Horrobin, D. F. and Stewart, C. Evening primrose oil and atopic eczema. Lancet 7-7-1990;336(8706):50. View abstract.
49239
Cameron, M., Gagnier, J. J., Little, C. V., Parsons, T. J., Blumle, A., and Chrubasik, S. Evidence of effectiveness of herbal medicinal products in the treatment of arthritis. Part 2: Rheumatoid arthritis. Phytother.Res 2009;23(12):1647-1662. View abstract.
49240
Bayles, B. and Usatine, R. Evening primrose oil. Am Fam.Physician 12-15-2009;80(12):1405-1408. View abstract.
49244
Kiss, A. K., Filipek, A., Czerwinska, M., and Naruszewicz, M. Oenothera paradoxa defatted seeds extract and its bioactive component penta-O-galloyl-beta-D-glucose decreased production of reactive oxygen species and inhibited release of leukotriene B4, interleukin-8, elastase, and myeloperoxidase in human neutrophils. J Agric.Food Chem 9-22-2010;58(18):9960-9966. View abstract.
49245
Jaszewska, E., Kosmider, A., Kiss, A. K., and Naruszewicz, M. Oenothera paradoxa defatted seeds extract containing pentagalloylglucose and procyanidins potentiates the cytotoxicity of vincristine. J Physiol Pharmacol 2010;61(5):637-643. View abstract.
49248
Cameron, M., Gagnier, J. J., and Chrubasik, S. Herbal therapy for treating rheumatoid arthritis. Cochrane Database Syst.Rev. 2011;(2):CD002948. View abstract.
49255
Mansel, R. E., Harrison, B. J., Melhuish, J., Sheridan, W., Pye, J. K., Pritchard, G., Maddox, P. R., Webster, D. J., and Hughes, L. E. A randomized trial of dietary intervention with essential fatty acids in patients with categorized cysts. Ann.N.Y.Acad.Sci. 1990;586:288-294. View abstract.
49257
Gateley, C. A., Maddox, P. R., Mansel, R. E., and Hughes, L. E. Mastalgia refractory to drug treatment. Br J Surg. 1990;77(10):1110-1112. View abstract.
49261
Gateley, C. A. and Mansel, R. E. Management of cyclical breast pain. Br.J Hosp.Med 1990;43(5):330-332. View abstract.
49262
Uccella, R., Contini, A., and Sartorio, M. [Action of evening primrose oil on cardiovascular risk factors in insulin-dependent diabetics]. Clin Ter. 6-15-1989;129(5):381-388. View abstract.
49263
Wade, V. A., Mansfield, P. R., and McDonald, P. J. Drug companies' evidence to justify advertising. Lancet 11-25-1989;2(8674):1261-1263. View abstract.
49264
Jantti, J., Nikkari, T., Solakivi, T., Vapaatalo, H., and Isomaki, H. Evening primrose oil in rheumatoid arthritis: changes in serum lipids and fatty acids. Ann.Rheum.Dis 1989;48(2):124-127. View abstract.
49268
Jamal, G. A., Carmichael, H., and Weir, A. I. Gamma-linolenic acid in diabetic neuropathy. Lancet 5-10-1986;1(8489):1098. View abstract.
49269
Meigel, W., Dettke, T., Meigel, E. M., and Lenze, U. [Additional oral therapy of atopic dermatitis with unsaturated fatty acids]. Z.Hautkr. 1987;62 Suppl 1:100-103. View abstract.
49271
Wolkin, A., Jordan, B., Peselow, E., Rubinstein, M., and Rotrosen, J. Essential fatty acid supplementation in tardive dyskinesia. Am J Psychiatry 1986;143(7):912-914. View abstract.
49272
Skogh, M. Atopic eczema unresponsive to evening primrose oil (linoleic and gamma- linolenic acids). J Am.Acad.Dermatol. 1986;15(1):114-115. View abstract.
49273
Biagi, P. L., Bordoni, A., Masi, M., Ricci, G., Fanelli, C., Patrizi, A., and Ceccolini, E. A long-term study on the use of evening primrose oil (Efamol) in atopic children. Drugs Exp Clin Res 1988;14(4):285-290. View abstract.
49274
Goodwin, P. J., Neelam, M., and Boyd, N. F. Cyclical mastopathy: a critical review of therapy. Br.J Surg. 1988;75(9):837-844. View abstract.
49275
van Doormaal, J. J., Idema, I. G., Muskiet, F. A., Martini, I. A., and Doorenbos, H. Effects of short-term high dose intake of evening primrose oil on plasma and cellular fatty acid compositions, alpha-tocopherol levels, and erythropoiesis in normal and type 1 (insulin-dependent) diabetic men. Diabetologia 1988;31(8):576-584. View abstract.
49276
el Ela, S. H., Prasse, K. W., Carroll, R., and Bunce, O. R. Effects of dietary primrose oil on mammary tumorigenesis induced by 7,12-dimethylbenz(a)anthracene. Lipids 1987;22(12):1041-1044. View abstract.
49277
Horrobin, D. F. Multiple sclerosis: the rational basis for treatment with colchicine and evening primrose oil. Med Hypotheses 1979;5(3):365-378. View abstract.
49278
Horrobin, D. F. Essential fatty acid and prostaglandin metabolism in Sjogren's syndrome, systemic sclerosis and rheumatoid arthritis. Scand.J Rheumatol.Suppl 1986;61:242-245. View abstract.
49279
Greaves, M. W. and Corbett, M. F. Treatment of atopic eczema with evening primrose oil. Br.J Dermatol. 1988;118(3):449-451. View abstract.
49281
Ferrando, J. [Clinical trial of a topical preparation containing urea, sunflower oil, evening primrose oil, wheat germ oil and sodium pyruvate, in several hyperkeratotic skin conditions]. Med Cutan.Ibero.Lat.Am 1986;14(2):133-137. View abstract.
49285
Guenther, L. and Wexler, D. Efamol in the treatment of atopic dermatitis. J Am Acad.Dermatol. 1987;17(5 Pt 1):860. View abstract.
49286
Bamford, J. T., Gibson, R. W., and Renier, C. M. Atopic eczema unresponsive to evening primrose oil (linoleic and gamma- linolenic acids). J Am.Acad.Dermatol. 1985;13(6):959-965. View abstract.
49288
Wright, S. and Burton, J. L. Oral evening-primrose-seed oil improves atopic eczema. Lancet 11-20-1982;2(8308):1120-1122. View abstract.
49290
Field, E. J. and Joyce, G. Effect of prolonged ingestion of gamma-linolenate by MS patients. Eur.Neurol. 1978;17(2):67-76. View abstract.
49293
Manku, M. S., Horrobin, D. F., Morse, N., Kyte, V., Jenkins, K., Wright, S., and Burton, J. L. Reduced levels of prostaglandin precursors in the blood of atopic patients: defective delta-6-desaturase function as a biochemical basis for atopy. Prostaglandins Leukot.Med 1982;9(6):615-628. View abstract.
49295
Horrobin, D. F. and Morse, P. F. Evening primrose oil and atopic eczema. Lancet 1-28-1995;345(8944):260-261. View abstract.
49297
Berth-Jones, J., Thompson, J., and Graham-Brown, R. A. Evening primrose oil and atopic eczema. Lancet 2-25-1995;345(8948):520. View abstract.
49302
Liu, H. and Zhou, J. F. [Xianbai buyang Huanwu decoction used for treating hypertension with kidney qi deficiency and blood stasis]. Zhongguo Zhong Xi Yi Jie He Za Zhi 1993;13(12):714-7, 707. View abstract.
49303
Wetzig, N. R. Mastalgia: a 3 year Australian study. Aust N Z J Surg 1994;64(5):329-331. View abstract.
49304
Engler, M. M. Comparative study of diets enriched with evening primrose, black currant, borage or fungal oils on blood pressure and pressor responses in spontaneously hypertensive rats. Prostaglandins Leukot.Essent.Fatty Acids 1993;49(4):809-814. View abstract.
49306
Joe, L. A. and Hart, L. L. Evening primrose oil in rheumatoid arthritis. Ann.Pharmacother. 1993;27(12):1475-1477. View abstract.
49307
Takahashi, R., Inoue, J., Ito, H., and Hibino, H. Evening primrose oil and fish oil in non-insulin-dependent-diabetes. Prostaglandins Leukot Essent Fatty Acids 1993;49(2):569-571. View abstract.
49308
Olsson, R., Tysk, C., Aldenborg, F., and Holm, B. Prolonged postpartum course of intrahepatic cholestasis of pregnancy. Gastroenterology 1993;105(1):267-271. View abstract.
49310
Sture, G. H. and Lloyd, D. H. Canine atopic disease: therapeutic use of an evening primrose oil and fish oil combination. Vet.Rec. 8-12-1995;137(7):169-170. View abstract.
49311
Chilton, S. A. Cognitive behaviour therapy for the chronic fatigue syndrome. Evening primrose oil and magnesium have been shown to be effective. BMJ 4-27-1996;312(7038):1096. View abstract.
49315
Newman, V., Rock, C. L., Faerber, S., Flatt, S. W., Wright, F. A., and Pierce, J. P. Dietary supplement use by women at risk for breast cancer recurrence. The Women's Healthy Eating and Living Study Group. J Am Diet.Assoc. 1998;98(3):285-292. View abstract.
49318
Engler, M. M., Schambelan, M., Engler, M. B., Ball, D. L., and Goodfriend, T. L. Effects of dietary gamma-linolenic acid on blood pressure and adrenal angiotensin receptors in hypertensive rats. Proc.Soc.Exp.Biol.Med. 1998;218(3):234-237. View abstract.
49319
Hounsom, L., Horrobin, D. F., Tritschler, H., Corder, R., and Tomlinson, D. R. A lipoic acid-gamma linolenic acid conjugate is effective against multiple indices of experimental diabetic neuropathy. Diabetologia 1998;41(7):839-843. View abstract.
49320
Martens-Lobenhoffer, J. and Meyer, F. P. Pharmacokinetic data of gamma-linolenic acid in healthy volunteers after the administration of evening primrose oil (Epogam). Int.J Clin Pharmacol Ther. 1998;36(7):363-366. View abstract.
49323
Callender K, McGregor M, and Kirk P. A double-blind trial of evening primrose oil in the premenstrual syndrome: nervous symptom subgroup. Hum Psychopharmacol 1988;3:57-61.
49324
Kruger, M. C., Coetzer, H., de Winter, R., Gericke, G., and van Papendorp, D. H. Calcium, gamma-linolenic acid and eicosapentaenoic acid supplementation in senile osteoporosis. Aging (Milano.) 1998;10(5):385-394.
49325
Papas, E. Mcoptom D. Dry Eye and Diet: What Research Says About Essential Fatty Acids. Contact Lens Spectrum. 2012;27(3):16-17.
49326
Barber A. Evening primrose oil: a panacea? Pharmaceutical J 1988;723-725.
49327
Horrobin, D. F. The importance of gamma-linolenic acid and prostaglandin E1 in human nutrition and medicine. Journal of Holistic Medicine. 1981;3(2):118-139.
49330
Poisson J, Germain-Bellenger S, Engler M, and et al. Gamma-linolenic acid: A pharmacological nutrient for hypertension? Abstracts from the International Symposium on Gamma Linolenic Acid, American Oil Chemists Society, Health and Nutrition Division Annual Conference, San Diego, CA, 2000.
49331
Engler MM. The hypotensive effect of dietary gamma-linolenic acid and associated alterations in tissue fatty acid composition and the Renin-Angiotensin system. Abstracts from the International Symposium on Gamma Linolenic Acid, American Oil Chemists Society, Health and Nutrition Division Annual Conference, San Diego, CA, 2000.
49332
Swapan S, Sabyasachi B Nath GD. Evening primrose oil in treatment of atopic dermatitis: A randomized placebo-controlled trial. Indian Journal of Dermatology, Venereology and Leprology. 2008;(2)
49335
Ockerman PA, Bachrack I, Glans S, and et al. Evening primrose oil as a treatment of premenstrual syndrome. Rec Adv Clin Nutr 1986;2:404-405.
49336
van der Merwe, C. F. Booyens J. A double-blind placebo controlled trial of evening primrose oil (linoleic and gamma-linolenic acid) in primary liver cancer [EASL abstract]. J Hepatol. 1988;7(1):S189.
49337
Thuluvath PJ, Triger DR Manku MS Morse-Fisher N. Evening primrose oil in the treatment of severe refractory biliary pruritus. Eur J Gastroenterology and Hepatology 1991;3(1):87-90.
49338
Preece PE, Hanslip JI Gilbert L. Evening primrose oil (Efamol) for mastalgia. In: Horrobin DF. Clinical Uses of Essential Fatty Acids . Montreal, Quebec: Eden;1982.
49339
Parveen, S. Sarwar G. Ali M. Channa G. A. Danazol versus oil of evening primrose in the treatment of mastalgia. Pakistan Journal of Surgery. 2007;23(1):10-13.
49340
Mansel RE, Pye JK Hughes LE. Effects of essential fatty acids on cyclical mastalgia and non-cyclical breast disorders. In: Horrobin DF. Omega-6 essential fatty acids: pathophysiology and roles in clinical medicine. New York: Wiley-Liss;1990.
49341
Ty-Torredes, K. A. The effect of oral evening primrose oil on bishop score and cervical length amongst term gravidas. Am J Obstet Gynecol. 2006;195(6 Suppl 1):S30.
49342
Anstey, A. Quigley M. Wilkinson J. D. Topical evening primrose oil as treatment for atopic eczema. J dermatol treat. 1990;1(4):199-201.
49344
Sholkens BA, Gehring D, Schlotte V, and et al. Evening Primrose oil, a dietary prostaglandin precursor diminishes vascular reactivity to resin and angiotensin II in rats. Prostagland Leukotrienes Med 1982;8:273-285.
49345
Garcia C, Carter J, and Chou A. Gamma linolenic acid causes weight loss and lower blood pressure in overweight patients with family history of obesity. Swed J Biol Med 1986;4:8-11.
49347
Tang W, Song YF He ZM. Clinical observation of Blackcurrant oil Soft Capsule and Evening primrose oil Soft Capsule in treating hyperlipidemia. Acta Chinese Medicine and Pharmacology 1993;21(4):37-38.
49350
Kiehl R, Ionescu G, Manuel P, and et al. Klinische, immun- und lipidmodulatorische effekte einer behandlung mit ungesattigten fettsauren bei atopischer dermatitis. Med.Leiter: J.Muller-Steinwachs 1994;69(1):42-48.
49351
Boehm, K. Pittler M. H. Wilson N. van Gool C. Humphreys R. Ernst E. Oral evening primrose oil and borage oil for atopic eczema. Cochrane Database Sys Rev 2009;(1):CD004416.
49352
Humphreys F, Symons J, Brown H, and et al. The effects of gamolenic acid on adult atopic eczema and premenstrual exacerbation of eczema. Eur.J.Dermatol. 1994;4(598):603.
49353
Centre for Reviews and Dissemination. Oral essential fatty acid supplementation in atopic dermatitis: a meta-analysis of placebo-controlled trials (Structured abstract). 2012;3
49354
Ferreira MJ, Fiadeiro T Silva M Soares AP. Topical gamma-linolenic acid therapy in atopic dermatitis: a clinical and biometric evaluation. Allergo J 1998;7(4):213-216.
49355
Centre for Reivews and Dissemination.
49356
Coskery G, Cowley N Allen R. The effect of dietary supplementation with evening primrose oil on skin surface texture in atopic dermatitis. J Investigative Dermatitis 1988;91(4):413.
49357
Campbell ID, Stewart JCM, Royle GT, Taylor I. A randomized controlled trial of EPO for mastalgia. In: Mansel RE (ed). Recent Developments in the Study of Benign Breast Disease. The Proceedings of the 4th International Benign Breast Symposium. Manchester, England, April 1991. pg 89-96.
49358
Pashby N, Mansel R, Hughes L, and et al. A clinical trial of evening primrose in mastalgia. Br J Surg 1981;68:801.
49359
Anonymous. Evening primrose hypertension hope. Central 1989;35
49360
Purewal TS, Evans PMS, Havard F, O'Hare JP. Lack of effect of evening primrose oil on autonomic function tests after 12 months of treatment. Diabetologia 1997;40(Suppl 1):A556, abstract 2186.
49361
Jones, L. Essential Fatty Acids and Dry Eye: What Do We Know? Contact Lens Spectrum 2009;24(7):14-15.
49362
Liu, L. Z. Wu Q. Liu P. J. Li G. Q. Bensoussan A. Kiat H. Chinese herbal medicines for hypertriglyceridemia. Cochrane Database Sys Rev 2012;(1):CD009560.
49363
Truelove SC, Witts LJ. Cortisone in ulcerative colitis. Final report of a therapeutic trial. Br Med J 1955;11:1041-1048.
49364
Bates D, Fawcett PRW, Shaw DA, and et all. Polyunsaturated fatty acids in treatment of acute remitting multiple sclerosis. Br Med J 1978;ii:1390-1391.
49365
Belch JJF, Shaw B, O'Dowd A, et al. Evening primrose oil (Efamol) as a treatment for cold-induced vasospasm (Raynaud's phenomenon). Prog Lipid Res 1986;25:335-40.
65864
Johnson, M., Ostlund, S., Fransson, G., Kadesjo, B., and Gillberg, C. Omega-3/omega-6 fatty acids for attention deficit hyperactivity disorder: a randomized placebo-controlled trial in children and adolescents. J.Atten.Disord. 2009;12(5):394-401. View abstract.
88182
Sharma N, Gupta A, Jha PK, Rajput P. Mastalgia cured! Randomized trial comparing centchroman to evening primrose oil (letter). The Breast Journal 2012;18(5):509-10.
88183
Rezapour-Firouzi S, Arefhosseini SR, Mehdi F, et al. Immunomodulatory and therapeutic effects of Hot-natured diet and co-supplemented hemp seed, evening primrose oils intervention in multiple sclerosis patients. Complement Ther Med 2013;21(5):473-80.
88184
Farzaneh F, Fatehi S, Sohrabi MR, Alizadeh K. The effect of oral evening primrose oil on menopausal hot flashes: a randomized clinical trial. Arch Gynecol Obstet 2013;288(5):1075-9.
88187
Puri BK. The safety of evening primrose oil in epilepsy. Prostaglandins Leukotrienes Essential Fatty Acids 2007;77:101-3.
93578
Jalloh MA, Gregory PJ, Hein D, et al. Dietary supplement interactions with antiretrovirals: a systematic review. Int J STD AIDS. 2017 Jan;28(1):4-15. View abstract.
96713
Jaafarnejad F, Abidmoghaddam E, Emami SA, Saki A. Compare the effect of flaxseed, evening primrose oil, and Vitamin E on duration of periodic breast pain. J Educ Health Promot. 2017 Oct 4;6:85. View abstract.
96714
Veselinovic M, Vasiljevic D, Vucic V, et al. Clinical benefits of n-3 PUFA and gamma-Linolenic acid in patients with rheumatoid arthritis. Nutrients. 2017 Mar 25;9(4). View abstract.
96715
Osman M, Badawi E. Evening primrose oil reducing serum lithium concentration. Ther Adv Psychopharmacol. 2016 Oct;6(5):343-44. View abstract.
96716
Kilic MO, Sen M, Icen D. The comparison of evening primrose oil, fructus agni casti, and reassurance in the treatment of mastalgia. Int J Surg Med. 2016;2(2):83-88.
96717
Kalati M, Kashanian M, Jahdi F, Naseri M, Haghani H, SHeikhansari N. Evening primrose oil and labour, is it effective? A randomized clinical trial. J Obstet Gynaecol. 2018 Feb 9:1-5. View abstract.
96718
Kwon HS, Lee JH, Kim GM, Choi EH, Bae JM. Topical evening primrose oil as a possible therapeutic alternative in children with molluscum contagiosum. Clin Exp Dermatol. 2017 Dec;42(8):923-25. View abstract.
96719
Jamilian M, Karamali M, ,Taghizadeh M, et al. Vitamin D and evening primrose oil administration improve glycemia and lipid profiles in women with gestational diabetes. Lipids. 2016 Mar;51(3):349-56. View abstract.
96720
Nasri K, Akrami S, Rahimim M, et al. The effects of vitamin D and evening primrose oil co-supplementation on lipid profiles and biomarkers of oxidative stress in vitamin D-deficient women with polycystic ovary syndrome: a randomized double-blind, placebo-controlled trial. Endocr Res. 2018 Feb;43(1):1-10. View abstract.
102556
Sharif SN, Darsareh F. Impact of evening primrose oil consumption on psychological symptoms of postmenopausal women: a randomized double-blinded placebo-controlled clinical trial. Menopause. 2020;27(2):194-198. View abstract.
104139
Khorshidi M, Zarezadeh M, Moradi Moghaddam O, et al. Effect of evening primrose oil supplementation on lipid profile: a systematic review and meta-analysis of randomized clinical trials. Phytother Res. 2020;34(10):2628-2638. Online ahead of print. View abstract.
104140
Balci FL, Uras C, Feldman S. Clinical factors affecting the therapeutic efficacy of evening primrose oil on mastalgia. Ann Surg Oncol. 2020;27(12):4844-4852. Online ahead of print. View abstract.
104685
No author. Expression of concern: The effects of vitamin D and evening primrose oil co-supplementation on lipid profiles and biomarkers of oxidative stress in vitamin D-deficient women with polycystic ovary syndrome: A randomized, double-blind, placebo-controlled trial. Endocr Res. 2021;46(1):44. View abstract.
105102
Rattanatantikul T, Maiprasert M, Sugkraroek P, Bumrungpert A. Efficacy and safety of nutraceutical on menopausal symptoms in post-menopausal women: A randomized, double-blind, placebo-controlled clinical trial. J Diet Suppl. 2020:1-15. View abstract.
109028
Hemmatzadeh S, Mohammad Alizadeh Charandabi S, Veisy A, Mirghafourvand M. Evening primrose oil for cervical ripening in term pregnancies: a systematic review and meta-analysis. J Complement Integr Med 2021. View abstract.
109029
Moradi M, Niazi A, Heydarian Miri H, Lopez V. The effect of evening primrose oil on labor induction and cervical ripening: A systematic review and meta-analysis. Phytother Res 2021;35(10):5374-5383. View abstract.
109426
Ahmad Adni LL, Norhayati MN, Mohd Rosli RR, Muhammad J. A Systematic Review and Meta-Analysis of the Efficacy of Evening Primrose Oil for Mastalgia Treatment. Int J Environ Res Public Health 2021;18(12):6295. View abstract.
109427
Safdari F, Motaghi Dastenaei B, Kheiri S, Karimiankakolaki Z. Effect of Evening Primrose Oil on Postmenopausal Psychological Symptoms: A Triple-Blind Randomized Clinical Trial. J Menopausal Med 2021;27(2):58-65. View abstract.
109428
Kazemi F, Masoumi SZ, Shayan A, Oshvandi K. The Effect of Evening Primrose Oil Capsule on Hot Flashes and Night Sweats in Postmenopausal Women: A Single-Blind Randomized Controlled Trial. J Menopausal Med 2021;27(1):8-14. View abstract.
109429
Moghadam MY, Nemat-Shahi M, Soroosh D, Nemat-Shahi M, Asadi A. Effect of evening primrose oil on postoperative pain after appendectomy: A double-blind, randomized, clinical trial. Biomedicine (Taipei) 2020;10(1):28-32. View abstract.
109430
Kazmierska A, Boleslawska I, Polanska A, et al. Effect of Evening Primrose Oil Supplementation on Selected Parameters of Skin Condition in a Group of Patients Treated with Isotretinoin-A Randomized Double-Blind Trial. Nutrients 2022;14(14):2980. View abstract.
110571
Mansour Ghanaei M, Asgharnia M, Farokhfar M, Mohammad Asgari Ghalebin S, Rafiei E, Haryalchi K. The effect of consuming evening primrose oil on cervical preparation before hysteroscopy: An RCT. Int J Reprod Biomed 2022;20(7):591-600. View abstract.
112129
Rahbar N, Sharafshahi F, Ghods S, Ghorbani R. Comparison of Misoprostol and Evening Primrose Oil on Cervical Preparation Before Gynecological Surgery. J Clin Pharmacol 2023. View abstract.
112130
Shahraki AD, Mirhoseini S, Movahedi M, Hajihashemy M, Haghollahi F. Comparative Study of the Effect of Vaginal use of Primrose Oil with Misoprostol on Cervical Preparation of Prim Gravid Women: A Double-blind Clinical Trial. Adv Biomed Res 2023;12:78. View abstract.
112131
Shahinfar S, Abedi P, Jahanfar S, Khajehpoor M, Chashmyazdan M. The effect of evening primrose oil on cervical ripening and birth outcomes: A systematic review and meta-analysis. Heliyon 2023;9(2):e13414. View abstract.
114806
Mahmoodinasab M, Loripoor M, Vazirinejad R, Aminzadeh F. Effect of misoprostol with and without evening primrose (Oenothera biennis) on induction of missed abortion. Avicenna J Phytomed 2023;13(5):454-462. View abstract.
114807
Ghavi F, Shakeri F, Farahnaz H, Abdolahian S. Comparison of the Effect of Fennel and Evening Primrose Oil on Menopausal Problems and Hormonal Levels: A Randomized Controlled Trial. Iran J Nurs Midwifery Res 2023;28(4):430-435. View abstract.
114808
Hashemi H, Hasanpoor-Azghady SB, Farahani M, Amiri-Farahani L. Comparison of the effect of vaginal misoprostol and evening primrose oil capsule with misoprostol alone on the consequences of abortion in women with intrauterine fetal death: a randomized clinical trial. BMC Complement Med Ther 2023;23(1):248. View abstract.
114809
Kumari J, Amrita, Sinha A, Kumari S, Biswas P, Poonam. Effectiveness of Evening Primrose and Vitamin E for Cyclical Mastalgia: A Prospective Study. Cureus 2024;16(4):e58055. View abstract.
114810
Ariana S, Amjadi N, Kazemi SN, Ahmadli Z. The Use of Evening Primrose Oil for Cervical Ripening in Low-Risk Women with Term Pregnancy: A Randomized Double-Blinded Controlled Trial. Complement Med Res 2024;31(3):215-221. View abstract.