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Chesnut, C. H., III, Silverman, S., Andriano, K., Genant, H., Gimona, A., Harris, S., Kiel, D., LeBoff, M., Maricic, M., Miller, P., Moniz, C., Peacock, M., Richardson, P., Watts, N., and Baylink, D. A randomized trial of nasal spray salmon calcitonin in postmenopausal women with established osteoporosis: the prevent recurrence of osteoporotic fractures study. PROOF Study Group. Am J Med. 2000;109(4):267-276. View abstract.

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Harris, S. T., Watts, N. B., Genant, H. K., McKeever, C. D., Hangartner, T., Keller, M., Chesnut, C. H., III, Brown, J., Eriksen, E. F., Hoseyni, M. S., Axelrod, D. W., and Miller, P. D. Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group. JAMA 10-13-1999;282(14):1344-1352. View abstract.

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McClung, M. R., Geusens, P., Miller, P. D., Zippel, H., Bensen, W. G., Roux, C., Adami, S., Fogelman, I., Diamond, T., Eastell, R., Meunier, P. J., and Reginster, J. Y. Effect of risedronate on the risk of hip fracture in elderly women. Hip Intervention Program Study Group. N.Engl.J.Med. 2-1-2001;344(5):333-340. View abstract.

Neer, R. M., Arnaud, C. D., Zanchetta, J. R., Prince, R., Gaich, G. A., Reginster, J. Y., Hodsman, A. B., Eriksen, E. F., Ish-Shalom, S., Genant, H. K., Wang, O., and Mitlak, B. H. Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis. N.Engl.J.Med. 5-10-2001;344(19):1434-1441. View abstract.

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Chesnut III, C. H., Skag, A., Christiansen, C., Recker, R., Stakkestad, J. A., Hoiseth, A., Felsenberg, D., Huss, H., Gilbride, J., Schimmer, R. C., and Delmas, P. D. Effects of oral ibandronate administered daily or intermittently on fracture risk in postmenopausal osteoporosis. J.Bone Miner.Res. 2004;19(8):1241-1249. View abstract.

Reginster, J. Y., Seeman, E., De Vernejoul, M. C., Adami, S., Compston, J., Phenekos, C., Devogelaer, J. P., Curiel, M. D., Sawicki, A., Goemaere, S., Sorensen, O. H., Felsenberg, D., and Meunier, P. J. Strontium ranelate reduces the risk of nonvertebral fractures in postmenopausal women with osteoporosis: Treatment of Peripheral Osteoporosis (TROPOS) study. J.Clin.Endocrinol.Metab 2005;90(5):2816-2822. View abstract.

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Spector, T. D., Conaghan, P. G., Buckland-Wright, J. C., Garnero, P., Cline, G. A., Beary, J. F., Valent, D. J., and Meyer, J. M. Effect of risedronate on joint structure and symptoms of knee osteoarthritis: results of the BRISK randomized, controlled trial [ISRCTN01928173]. Arthritis Res.Ther. 2005;7(3):R625-R633. View abstract.

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Cheung, K. M., Lu, W. W., Luk, K. D., Wong, C. T., Chan, D., Shen, J. X., Qiu, G. X., Zheng, Z. M., Li, C. H., Liu, S. L., Chan, W. K., and Leong, J. C. Vertebroplasty by use of a strontium-containing bioactive bone cement. Spine (Phila Pa 1976.) 9-1-2005;30(17 Suppl):S84-S91. View abstract.

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Roux, C., Reginster, J. Y., Fechtenbaum, J., Kolta, S., Sawicki, A., Tulassay, Z., Luisetto, G., Padrino, J. M., Doyle, D., Prince, R., Fardellone, P., Sorensen, O. H., and Meunier, P. J. Vertebral fracture risk reduction with strontium ranelate in women with postmenopausal osteoporosis is independent of baseline risk factors. J.Bone Miner.Res. 2006;21(4):536-542. View abstract.

Bellamy, N., Campbell, J., Robinson, V., Gee, T., Bourne, R., and Wells, G. Viscosupplementation for the treatment of osteoarthritis of the knee. Cochrane.Database.Syst.Rev. 2006;(2):CD005321. View abstract.

Seeman, E., Vellas, B., Benhamou, C., Aquino, J. P., Semler, J., Kaufman, J. M., Hoszowski, K., Varela, A. R., Fiore, C., Brixen, K., Reginster, J. Y., and Boonen, S. Strontium ranelate reduces the risk of vertebral and nonvertebral fractures in women eighty years of age and older. J.Bone Miner.Res. 2006;21(7):1113-1120. View abstract.

O'Donnell, S., Cranney, A., Wells, G. A., Adachi, J. D., and Reginster, J. Y. Strontium ranelate for preventing and treating postmenopausal osteoporosis. Cochrane.Database.Syst.Rev. 2006;3:CD005326. View abstract.

Medina, J. M., Thomas, A., and Denegar, C. R. Knee osteoarthritis: should your patient opt for hyaluronic acid injection? J.Fam.Pract. 2006;55(8):669-675. View abstract.

Hollriegl, V., Li, W. B., and Oeh, U. Human biokinetics of strontium--part II: Final data evaluation of intestinal absorption and urinary excretion of strontium in human subjects after stable tracer administration. Radiat.Environ.Biophys. 2006;45(3):179-185. View abstract.

Rintelen, B., Neumann, K., and Leeb, B. F. A meta-analysis of controlled clinical studies with diacerein in the treatment of osteoarthritis. Arch.Intern.Med. 9-25-2006;166(17):1899-1906. View abstract.

Manicourt, D. H., Azria, M., Mindeholm, L., Thonar, E. J., and Devogelaer, J. P. Oral salmon calcitonin reduces Lequesne's algofunctional index scores and decreases urinary and serum levels of biomarkers of joint metabolism in knee osteoarthritis. Arthritis Rheum. 2006;54(10):3205-3211. View abstract.

Bingham, C. O., III, Buckland-Wright, J. C., Garnero, P., Cohen, S. B., Dougados, M., Adami, S., Clauw, D. J., Spector, T. D., Pelletier, J. P., Raynauld, J. P., Strand, V., Simon, L. S., Meyer, J. M., Cline, G. A., and Beary, J. F. Risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression in patients with medial compartment osteoarthritis of the knee: results of the two-year multinational knee osteoarthritis structural arthritis study. Arthritis Rheum. 2006;54(11):3494-3507. View abstract.

Naess, I. A., Christiansen, S. C., Romundstad, P., Cannegieter, S. C., Rosendaal, F. R., and Hammerstrom, J. Incidence and mortality of venous thrombosis: a population-based study. J.Thromb.Haemost. 2007;5(4):692-699. View abstract.

Black, D. M., Delmas, P. D., Eastell, R., Reid, I. R., Boonen, S., Cauley, J. A., Cosman, F., Lakatos, P., Leung, P. C., Man, Z., Mautalen, C., Mesenbrink, P., Hu, H., Caminis, J., Tong, K., Rosario-Jansen, T., Krasnow, J., Hue, T. F., Sellmeyer, D., Eriksen, E. F., and Cummings, S. R. Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis. N.Engl.J.Med. 5-3-2007;356(18):1809-1822. View abstract.

Bruyere, O., Roux, C., Detilleux, J., Slosman, D. O., Spector, T. D., Fardellone, P., Brixen, K., Devogelaer, J. P., Diaz-Curiel, M., Albanese, C., Kaufman, J. M., Pors-Nielsen, S., and Reginster, J. Y. Relationship between bone mineral density changes and fracture risk reduction in patients treated with strontium ranelate. J.Clin.Endocrinol.Metab 2007;92(8):3076-3081. View abstract.

Reginster, J. Y. The efficacy of glucosamine sulfate in osteoarthritis: financial and nonfinancial conflict of interest. Arthritis Rheum 2007;56(7):2105-2110. View abstract.

Vlad, S. C., LaValley, M. P., McAlindon, T. E., and Felson, D. T. Glucosamine for pain in osteoarthritis: why do trial results differ? Arthritis Rheum 2007;56(7):2267-2277. View abstract.

Roux, C., Fechtenbaum, J., Kolta, S., Briot, K., and Girard, M. Mild prevalent and incident vertebral fractures are risk factors for new fractures. Osteoporos.Int. 2007;18(12):1617-1624. View abstract.

Malaise, O., Bruyere, O., and Reginster, J. Y. Strontium ranelate normalizes bone mineral density in osteopenic patients. Aging Clin.Exp.Res. 2007;19(4):330-333. View abstract.

Marquis, P., Roux, C., de la Loge, C., Diaz-Curiel, M., Cormier, C., Isaia, G., Badurski, J., Wark, J., and Meunier, P. J. Strontium ranelate prevents quality of life impairment in post-menopausal women with established vertebral osteoporosis. Osteoporos.Int. 2008;19(4):503-510. View abstract.

Bruyere, O., Delferriere, D., Roux, C., Wark, J. D., Spector, T., Devogelaer, J. P., Brixen, K., Adami, S., Fechtenbaum, J., Kolta, S., and Reginster, J. Y. Effects of strontium ranelate on spinal osteoarthritis progression. Ann.Rheum.Dis. 2008;67(3):335-339. View abstract.

Seeman, E., Devogelaer, J. P., Lorenc, R., Spector, T., Brixen, K., Balogh, A., Stucki, G., and Reginster, J. Y. Strontium ranelate reduces the risk of vertebral fractures in patients with osteopenia. J.Bone Miner.Res. 2008;23(3):433-438. View abstract.

Reichenbach, S., Blank, S., Rutjes, A. W., Shang, A., King, E. A., Dieppe, P. A., Juni, P., and Trelle, S. Hylan versus hyaluronic acid for osteoarthritis of the knee: a systematic review and meta-analysis. Arthritis Rheum. 12-15-2007;57(8):1410-1418. View abstract.

Lyles, K. W., Colon-Emeric, C. S., Magaziner, J. S., Adachi, J. D., Pieper, C. F., Mautalen, C., Hyldstrup, L., Recknor, C., Nordsletten, L., Moore, K. A., Lavecchia, C., Zhang, J., Mesenbrink, P., Hodgson, P. K., Abrams, K., Orloff, J. J., Horowitz, Z., Eriksen, E. F., and Boonen, S. Zoledronic Acid in Reducing Clinical Fracture and Mortality after Hip Fracture. N.Engl.J.Med. 2007;357:nihpa40967. View abstract.

Reginster, J. Y., Felsenberg, D., Boonen, S., Diez-Perez, A., Rizzoli, R., Brandi, M. L., Spector, T. D., Brixen, K., Goemaere, S., Cormier, C., Balogh, A., Delmas, P. D., and Meunier, P. J. Effects of long-term strontium ranelate treatment on the risk of nonvertebral and vertebral fractures in postmenopausal osteoporosis: Results of a five-year, randomized, placebo-controlled trial. Arthritis Rheum. 2008;58(6):1687-1695. View abstract.

Rozhinskaia, L. I., Arapova, S. D., Dzeranova, L. K., Molitvoslovova, N. N., Marova, E. I., Il'in, A. V., Benevolenskaia, L. I., Nikitinskaia, O. A., Korotkova, T. A., Toroptsova, N. V., Smirnov, A. V., Demin, N. V., Rodionova, S. S., Buklemeshev, IuV, and Shumskii, A. A. [Efficacy and safety of bivalos therapy for postmenopausal osteoporosis. Results of Russian multicenter trial]. Ter.Arkh. 2008;80(5):47-52. View abstract.

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Roux, C., Fechtenbaum, J., Kolta, S., Isaia, G., Andia, J. B., and Devogelaer, J. P. Strontium ranelate reduces the risk of vertebral fracture in young postmenopausal women with severe osteoporosis. Ann.Rheum.Dis. 2008;67(12):1736-1738. View abstract.

Hwang, J. S., Chen, J. F., Yang, T. S., Wu, D. J., Tsai, K. S., Ho, C., Wu, C. H., Su, S. L., Wang, C. J., and Tu, S. T. The effects of strontium ranelate in Asian women with postmenopausal osteoporosis. Calcif.Tissue Int. 2008;83(5):308-314. View abstract.

Kobler, A., Kub, O., Schaller, H. G., and Gernhardt, C. R. Clinical effectiveness of a strontium chloride- containing desensitizing agent over 6 months: a randomized, double-blind, placebo-controlled study. Quintessence.Int. 2008;39(4):321-325. View abstract.

Meunier, P. J., Roux, C., Ortolani, S., Diaz-Curiel, M., Compston, J., Marquis, P., Cormier, C., Isaia, G., Badurski, J., Wark, J. D., Collette, J., and Reginster, J. Y. Effects of long-term strontium ranelate treatment on vertebral fracture risk in postmenopausal women with osteoporosis. Osteoporos.Int. 2009;20(10):1663-1673. View abstract.

Anastasilakis, A. D., Polyzos, S. A., Avramidis, A., Papatheodorou, A., and Terpos, E. Effect of strontium ranelate on lumbar spine bone mineral density in women with established osteoporosis previously treated with teriparatide. Horm.Metab Res. 2009;41(7):559-562. View abstract.

Barenholdt, O., Kolthoff, N., and Nielsen, S. P. Effect of long-term treatment with strontium ranelate on bone strontium content. Bone 2009;45(2):200-206. View abstract.

Liu, J. M., Wai-Chee, Kung A., Pheng, C. S., Zhu, H. M., Zhang, Z. L., Wu, Y. Y., Xu, L., Meng, X. W., Huang, M. L., Chung, L. P., Hussain, N. H., Sufian, S. S., and Chen, J. L. Efficacy and safety of 2 g/day of strontium ranelate in Asian women with postmenopausal osteoporosis. Bone 2009;45(3):460-465. View abstract.

Boivin, G., Farlay, D., Khebbab, M. T., Jaurand, X., Delmas, P. D., and Meunier, P. J. In osteoporotic women treated with strontium ranelate, strontium is located in bone formed during treatment with a maintained degree of mineralization. Osteoporos.Int. 2010;21(4):667-677. View abstract.

Reginster, J. Y., Bruyere, O., Sawicki, A., Roces-Varela, A., Fardellone, P., Roberts, A., and Devogelaer, J. P. Long-term treatment of postmenopausal osteoporosis with strontium ranelate: results at 8 years. Bone 2009;45(6):1059-1064. View abstract.

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Rizzoli, R., Laroche, M., Krieg, M. A., Frieling, I., Thomas, T., Delmas, P., and Felsenberg, D. Strontium ranelate and alendronate have differing effects on distal tibia bone microstructure in women with osteoporosis. Rheumatol.Int. 2010;30(10):1341-1348. View abstract.

Busse, B., Jobke, B., Hahn, M., Priemel, M., Niecke, M., Seitz, S., Zustin, J., Semler, J., and Amling, M. Effects of strontium ranelate administration on bisphosphonate-altered hydroxyapatite: Matrix incorporation of strontium is accompanied by changes in mineralization and microstructure. Acta Biomater. 2010;6(12):4513-4521. View abstract.

Mason, S., Hughes, N., Sufi, F., Bannon, L., Maggio, B., North, M., and Holt, J. A comparative clinical study investigating the efficacy of a dentifrice containing 8% strontium acetate and 1040 ppm fluoride in a silica base and a control dentifrice containing 1450 ppm fluoride in a silica base to provide immediate relief of dentin hypersensitivity. J.Clin.Dent. 2010;21(2):42-48. View abstract.

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Ananthraman, J. and Shahani, S. N. Clinical management of dentin hypersensitivity using cathode and anode iontophoresis. Fed.Oper.Dent. 1990;1(1):19-23. View abstract.

Kanis, J. A., Johansson, H., Oden, A., and McCloskey, E. V. A meta-analysis of the effect of strontium ranelate on the risk of vertebral and non-vertebral fracture in postmenopausal osteoporosis and the interaction with FRAX((R)). Osteoporos.Int. 2011;22(8):2347-2355. View abstract.

Doublier, A., Farlay, D., Khebbab, M. T., Jaurand, X., Meunier, P. J., and Boivin, G. Distribution of strontium and mineralization in iliac bone biopsies from osteoporotic women treated long-term with strontium ranelate. Eur.J.Endocrinol. 2011;165(3):469-476. View abstract.

Roque, I. Figuls, Martinez-Zapata, M. J., Scott-Brown, M., and Alonso-Coello, P. Radioisotopes for metastatic bone pain. Cochrane.Database.Syst.Rev. 2011;(7):CD003347. [RETRACTED]. View abstract.

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Olson, B. L., McDonald, J. L., Jr., and Stookey, G. K. The effect of strontium and fluoride upon in vitro plaque and rat caries. J.Dent.Res. 1978;57(9-10):903. View abstract.

Blake, G. M., Zivanovic, M. A., McEwan, A. J., and Ackery, D. M. Sr-89 therapy: strontium kinetics in disseminated carcinoma of the prostate. Eur.J.Nucl.Med. 1986;12(9):447-454. View abstract.

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Robinson, R. G., Spicer, J. A., Preston, D. F., Wegst, A. V., and Martin, N. L. Treatment of metastatic bone pain with strontium-89. Int.J.Rad.Appl.Instrum.B 1987;14(3):219-222. View abstract.

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Collins, J. F. and Perkins, L. Clinical evaluation of the effectiveness of three dentifrices in relieving dentin sensitivity. J.Periodontol. 1984;55(12):720-725. View abstract.

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Liberman, U. A., Weiss, S. R., Broll, J., Minne, H. W., Quan, H., Bell, N. H., Rodriguez-Portales, J., Downs, R. W., Jr., Dequeker, J., and Favus, M. Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis. The Alendronate Phase III Osteoporosis Treatment Study Group. N.Engl.J.Med. 11-30-1995;333(22):1437-1443. View abstract.

Pearce, N. X., Addy, M., and Newcombe, R. G. Dentine hypersensitivity: a clinical trial to compare 2 strontium densensitizing toothpastes with a conventional fluoride toothpaste. J.Periodontol. 1994;65(2):113-119. View abstract.

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Black, D. M., Cummings, S. R., Karpf, D. B., Cauley, J. A., Thompson, D. E., Nevitt, M. C., Bauer, D. C., Genant, H. K., Haskell, W. L., Marcus, R., Ott, S. M., Torner, J. C., Quandt, S. A., Reiss, T. F., and Ensrud, K. E. Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group. Lancet 12-7-1996;348(9041):1535-1541. View abstract.

Silverstein, M. D., Heit, J. A., Mohr, D. N., Petterson, T. M., O'Fallon, W. M., and Melton, L. J., III. Trends in the incidence of deep vein thrombosis and pulmonary embolism: a 25-year population-based study. Arch.Intern.Med. 3-23-1998;158(6):585-593. View abstract.

Spets-Happonen, S., Seppa, L., Korhonen, A., and Alakuijala, P. Accumulation of strontium and fluoride in approximal dental plaque and changes in plaque microflora after rinsing with chlorhexidine-fluoride-strontium solution. Oral Dis. 1998;4(2):114-119. View abstract.

Cummings, S. R., Black, D. M., Thompson, D. E., Applegate, W. B., Barrett-Connor, E., Musliner, T. A., Palermo, L., Prineas, R., Rubin, S. M., Scott, J. C., Vogt, T., Wallace, R., Yates, A. J., and LaCroix, A. Z. Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures: results from the Fracture Intervention Trial. JAMA 12-23-1998;280(24):2077-2082. View abstract.

Recker R, Stakkestad J Weber T et al. Nonvertebral fracture benefit from oral ibandronate administered daily or with a unique drug-free interval: Results from a pivotal phase III study in postmenopausal osteoporosis (PMO). J BoneMiner Res 2002;17 [Suppl 1](S35)

Cummings SR, McClung MR Christiansen C et al. A phase III study of the effects of denosumab on vertebral, nonvertebral, and hip fracture in women with osteoporosis: results from the FREEDOM trial [Abstract 1286]. J Bone Miner Res 2008;23(S80)

Kaufman JM, Audran M, Bianchi G, et al. Efficacy and safety of strontium ranelate in the treatment of osteoporosis in men. J Clin Endocrinol Metab. 2013 Feb;98(2):592-601. doi: 10.1210/jc.2012-3048. View abstract.

Moise H, Chettle DR, Pejovic-Milic A. Monitoring bone strontium intake in osteoporotic females self-supplementing with strontium citrate with a novel in-vivo X-ray fluorescence based diagnostic tool. Bone. 2014 Apr;61:48-54. doi: 10.1016/j.bone.2014.01.002. View abstract.

Papoiu AD, Valdes-Rodriguez R, Nattkemper LA, Chan YH, Hahn GS, Yosipovitch G. A novel topical formulation containing strontium chloride significantly reduces the intensity and duration of cowhage-induced itch. Acta Derm Venereol. 2013 Sep 4;93(5):520-6. doi: 10.2340/00015555-1564. View abstract.

Scaglione M, Fabbri L, Casella F, Guido G. Strontium ranelate as an adjuvant for fracture healing: clinical, radiological, and ultrasound findings in a randomized controlled study on wrist fractures. Osteoporos Int. 2016 Jan;27(1):211-8. doi: 10.1007/s00198-015-3266-z. View abstract.

Reginster JY, Badurski J, Bellamy N, Bensen W, Chapurlat R, Chevalier X, Christiansen C, Genant H, Navarro F, Nasonov E, Sambrook PN, Spector TD, Cooper C. Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial. Ann Rheum Dis. 2013 Feb;72(2):179-86. doi: 10.1136/annrheumdis-2012-202231. View abstract.

Bruyère O, Reginster JY, Bellamy N, et al. Clinically meaningful effect of strontium ranelate on symptoms in knee osteoarthritis: a responder analysis. Rheumatology (Oxford). 2014 Aug;53(8):1457-64. doi: 10.1093/rheumatology/keu018. View abstract.

Pelletier JP, Roubille C, Raynauld JP, et al. Disease-modifying effect of strontium ranelate in a subset of patients from the Phase III knee osteoarthritis study SEKOIA using quantitative MRI: reduction in bone marrow lesions protects against cartilage loss. Ann Rheum Dis. 2015 Feb;74(2):422-9. doi: 10.1136/annrheumdis-2013-203989. View abstract.

Middleton ET, Steel SA, Aye M, Doherty SM. The effect of prior bisphosphonate therapy on the subsequent therapeutic effects of strontium ranelate over 2 years. Osteoporosis Int. 2012;23(1):295-303. doi: 10.1007/s00198-011-1547-8. View abstract.

Rizzoli R, Chapurlat RD, Laroche JM, et al. Effects of strontium ranelate and alendronate on bone microstructure in women with osteoporosis. Results of a 2-year study. Osteoporosis Int. 2012. 23(1):305-315. doi: 10.1007/s00198-011-1758-z. View abstract.

Seeman E, Boonen S, Borgström F, et al. Five years treatment with strontium ranelate reduces vertebral and nonvertebral fractures and increases the number and quality of remaining life-years in women over 80 years of age. Bone. 2010;46(4):1038-1042. doi: 10.1016/j.bone.2009.12.006. View abstract.

Reginster JY, Kaufman JM, Goemaere S, et al. Maintenance of antifracture efficacy over 10 years with strontium ranelate in postmenopausal osteoporosis. Osteoporos Int. 2012;23(3):1115-1122. doi: 10.1007/s00198-011-1847-z. View abstract.

[No authors listed]. Strontium ranelate discontinued. Drug Ther Bull. 2017 Aug;55(8):93-94. View abstract.

Protos [Product Information]. Available at: http://www.guildlink.com.au/gc/ws/servier/pi.cfm?product=sepproto. Accessed May 1, 2018.

Peng H, Yao F, Xiong S, Wu Z, Niu G, Lu T. Strontium in public drinking water and associated public health risks in Chinese cities. Environ Sci Pollut Res Int 2021;28(18):23048-23059. View abstract.

Tapee Tea contains hidden drug ingredients. FDA Medication Health Fraud. August 31, 2023. https://www.fda.gov/drugs/medication-health-fraud/tapee-tea-contains-hidden-drug-ingredients. Accessed September 14, 2023.