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Dynamic Technical Formulations, LLC. Issues a Voluntary Nationwide Recall of Tri-Ton Due to the Presence of Andarine and Ostarine. FDA Recalls, Market Withdrawals, & Safety Alerts, May 19, 2017. https://www.fda.gov/Safety/Recalls/ucm559700.htm?source=govdelivery&utm_medium=email&utm_source=govdelivery. Accessed: Sept 7, 2017.
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Warning Letter: Ironmag Labs 10/23/17. FDA Inspections, Compliance, Enforcement, and Criminal Investigations, October 23, 2017. https://www.fda.gov/iceci/enforcementactions/warningletters/2017/ucm582464.htm Accessed: November 1, 2017
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Coss CC, Jones A, Dalton JT. Pharmacokinetic drug interactions of the selective androgen receptor modulator GTx-024 (enobosarm) with itraconazole, rifampin, probenecid, celecoxib and rosuvastatin. Invest New Drugs 2016;34(4):458-67.
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Dubois V, Simitsidellis I, Laurent MR, et al. Enobosarm (GTx-024) modulates adult skeletal muscle mass independently of the androgen receptor in the satellite cell lineage. Endocrinology 2015;156(12):4522-33.
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Van Wagoner RM, Eichner A, Bhasin S, Deuster PA, Eichner D. Chemical composition and labeling of substances marketed as selective androgen receptor modulators and sold via the internet.
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Thevis M, Geyer H, Thomas A, Schänzer W. Trafficking of drug candidates relevant for sports drug testing: detection of non-approved therapeutics categorized as anabolic and gene doping agents in products distributed via the Internet. Drug Test Anal 2011;3(5):331-6.
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Dart DA, Kandil S, Tommasini-Ghelfi S, et al. Novel trifluoromethylated enobosarm analogues with potent antiandrogenic activity in vitro and tissue selectivity in vivo. Mol Cancer Ther 2018;17(9):1846-58.
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Leciejewska N, Pruszynska-Oszmalek E, Bien J, Nogowski L, Kolodziejski PA. Effect of ostarine (enobosarm/GTX024), a selective androgen receptor modulator, on adipocyte metabolism in Wistar rats. J Physiol Pharmacol 2019;70(4).
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106194
Roch PJ, Henkies D, Carstens JC, et al. Ostarine and ligandrol improve muscle tissue in an ovariectomized rat model. Front Endocrinol (Lausanne) 2020;11:556581.
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Komrakova M, Furtwängler J, Hoffmann DB, Lehmann W, Schilling AF, Sehmisch S. The selective androgen receptor modulator ostarine improves bone healing in ovariectomized rats. Calcif Tissue Int 2020;106(2):147-157.
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106196
Komrakova M, Nagel J, Hoffmann DB, Lehmann W, Schilling AF, Sehmisch S. Effect of selective androgen receptor modulator enobosarm on bone healing in a rat model for aged male osteoporosis. Calcif Tissue Int 2020;107(6):593-602.
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106197
Bedi H, Hammond C, Sanders D, Yang HM, Yoshida EM. Drug-induced liver injury from enobosarm (ostarine), a selective androgen receptor modulator. ACG Case Rep J 2021;8(1):e00518.
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Kintz P, Gheddar L, Paradis C, et al. Peroxisome Proliferator-Activated Receptor Delta Agonist (PPAR- d) and Selective Androgen Receptor Modulator (SARM) Abuse: Clinical, Analytical and Biological Data in a Case Involving a Poisonous Combination of GW1516 (Cardarine) and MK2866 (Ostarine). Toxics 2021;9(10):251.
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111383
Gheddar L, Raul JS, Kintz P. Development and validation of SARMs and metabolic modulators screening in hair using UHPLC-MS/MS: Application to a doping case and first identification of S23 in authentic human hair. J Chromatogr B Analyt Technol Biomed Life Sci 2021;1187:123048.
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111384
Komrakova M, Büchler G, Böker KO, et al. A combined treatment with selective androgen and estrogen receptor modulators prevents bone loss in orchiectomized rats. J Endocrinol Invest 2022;45(12):2299-2311.
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111385
Weinblatt D, Roy S. Drug-Induced Liver Injury Secondary to Enobosarm: A Selective Androgen Receptor Modulator. J Med Cases 2022;13(5):244-248.
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111386
Leciejewska N, Kolodziejski PA, Sassek M, Nogowski L, Malek E, Pruszynska-Oszmalek E. Ostarine-Induced Myogenic Differentiation in C2C12, L6, and Rat Muscles. Int J Mol Sci 2022;23(8):4404.
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111387
Roch PJ, Wolgast V, Gebhardt MM, et al. Combination of selective androgen and estrogen receptor modulators in orchiectomized rats. J Endocrinol Invest 2022;45(8):1555-1568.
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